200+ applicants

Company

Original Job Post

NextRNA Therapeutics · 2 days ago

Computational Biologist

Boston, MA

Full-time

Onsite

Senior Level

5+ years exp

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H1B Sponsorship

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Responsibilities

Target Discovery: Collaborate with drug development teams to integrate bioinformatics analyses into target discovery processes. Provide insights into potential therapeutic targets based on genomics and transcriptomics data, contributing to the overall drug development strategy.

NGS Data Analysis: Lead and contribute to the design and execution of bioinformatics pipelines for the analysis of NGS data, with a specific emphasis on RNA-seq datasets. Implement and optimize workflows for processing large-scale genomics and transcriptomics data.

RNA Biology Expertise: Utilize deep knowledge in RNA biology to interpret complex sequencing data, including differential gene expression, alternative splicing, and non-coding RNA analysis. Contribute to the development of novel approaches for integrative analysis of multi-omics data.

Translational Computational Biology: Bridge the gap between target discovery and clinical applications, translating molecular insights into innovative therapeutic strategies. Effectively communicate translational insights to key stakeholders.

Qualification

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Computational BiologyDrug DiscoveryTarget DiscoveryOncologyNeurologyRNA BiologyOmics SequencingR ProgrammingPython ProgrammingGithubNextflowAWSServer Infrastructure

Required

PhD degree in computational biology, bioinformatics, or a related field. + 5 years of industry

Early stage computationally/data driven target discovery experience is required.

Demonstrable experience of working with early drug discovery team/programs.

Relevant experience in disease areas such as oncology and/or neurology required.

Knowledge on RNA biology is required (gene regulation at isoform level).

Experience with multi-omics-sequencing data is required.

Experience with building and supporting bioinformatics pipelines.

Experience with statistical modeling and machine learning.

Experience with programming languages (R and python), code pipeline management (Github and Nextflow) and server infrastructure (AWS) is required.

Company

NextRNA Therapeutics

NextRNA Therapeutics creates targeted therapeutics with the aim of discovering novel ncRNAs that cause disease.

Founded in 2020

Cambridge, Massachusetts, USA

11-50 employees

https://www.nextrnatx.com

H1B Sponsorship

NextRNA Therapeutics has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Trends of Total Sponsorships

2022 (3)

2021 (2)