43 applicants

Company

Original Job Post

Sanofi · 3 days ago

Senior Scientist Crystallization

Cambridge, MA

Full-time

Onsite

Senior Level

2+ years exp

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Responsibilities

Work with internal partners to select the API physical form for new NCEs, considering manufacturability and scalability.

Develop processes for consistent production of API with required quality attributes using batch and continuous platforms.

Apply domain knowledge in Crystallization Engineering and Solid-State Chemistry to control API physiochemical properties.

Conduct physiochemical analysis and experimentation to understand processes and characterize products.

Lead Tech Transfer of crystallization to Pilot Plant and Manufacturing, including support for technical and HSE risk assessments.

Provide technical presentations, document work, and establish external collaborations to address scientific gaps.

Qualification

Find out how your skills align with this job's requirements. If anything seems off, you can easily click on the tags to select or unselect skills to reflect your actual expertise.

Crystallization developmentLab experimental designPATHPLCGCNMRModeling gPROMSModeling DynoChemModeling MatlabModeling PythonMultivariate AnalysisChemometricsStatisticsContinuous process scale-upTeamworkProblem-solvingInnovative

Required

PhD in Chemical engineering, Solid State Chemistry with a minimum of 2 year experience in industry or academia or a master’s degree with a minimum of 6 years of experience.

Proven track record in crystallization development.

An ability to work as part of a team, engaging other scientists with complementary skill sets in the field of pharmaceutical development.

A change agent mentality, proposing novel approach to challenging scientific questions and exploring new modeling approaches.

Ability to design and deliver lab experimental plans for crystallization process development including use of typical process and analytical experiment.

Familiar with PAT and common off-line analytical technics such as HPLC, GC and NMR.

Modeling experience using gPROMS, DynoChem, Matlab, Python or similar programming languages.

Some knowledge in Multivariate Analysis, chemometrics and statistics.

Experience in the development and scale-up of continuous processes.

Preferred

Domestic and international travel may be required (5-10%).

Company

Sanofi

Glassdoor

4.0

Sanofi is a healthcare company that provides treatments and the protection of life-saving vaccines.

Founded in 1973

Paris, Ile-de-France, FRA

10,001+ employees

https://www.sanofi.com

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