43 applicants

Company

Original Job Post

Sanofi · 2 days ago

Senior Data Scientist - Process Modeling

Framingham, MA

Full-time

Hybrid

Senior Level

5+ years exp

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Responsibilities

As part of matrix project teams, develop and deploy mechanistic, hybrid and data-driven modelling solutions to support downstream process development activities for a broad range of biopharmaceuticals.

Use programming languages such as Python, MATLAB, R to translate complex mathematical models into clean and reusable codes for model use and implementation.

In coordination with the process development group and working closely with the Data Science team, design and analyze targeted experiments required to calibrate and verify model performance.

Act as a change agent to support the implementation of process modelling in established process development workflows for targeted downstream unit operations.

Document progress against deliverables with rigorous scientific communication via technical presentations, reports and, when appropriate, scientific publications.

Track progress against deliverables and maintain a communication plan with key stakeholders and partners across departments.

For this position, domain knowledge in biologics downstream process development and manufacturing (e.g. affinity/ion exchange chromatography, filtration etc.) is required.

Qualification

Find out how your skills align with this job's requirements. If anything seems off, you can easily click on the tags to select or unselect skills to reflect your actual expertise.

Process ModelingDownstream OperationsBiologicsMathematical ModelingProgramming LanguagesMATLABRPythonBiologyMachine LearningMultivariate AnalysisProcess Simulation SoftwareGPROMSDSPXModel Predictive ControlProblem-SolvingCommunication

Required

Process systems engineer/modeler with a PhD in Chemical/Biochemical Engineering and a minimum of 5 years of industrial experience, or MSc with 9 years of industrial experience.

Proven track record of developing process models for downstream unit operations for biologics, e.g., affinity/ion exchange chromatography, ultra/ nano / tangential flow filtration etc. for process design, scale-up, scale-down and/or process control purposes.

Demonstrated ability to translate mathematical models into computer programs using programming languages such as MATLAB, R, Python or similar.

Domain knowledge in Biology with industrial or academic experience in downstream process development and/or manufacturing.

Excellent communication skills in an international environment.

Demonstrated knowledge and application of Machine Learning / Multivariate analysis methodologies to biological processes.

Knowledge/ experience with process simulation software (e.g. gPROMS, DSPX) and integrated systems modelling applications (i.e. flowsheet modelling).

Experience in continuous bioprocess manufacture with associated Model Predictive Control (MPC).

Solid track record of publications in the field of process modelling/process simulation in peer-reviewed journals.

Benefits

Healthcare benefits

Wellness programs

Parental leave

Company

Sanofi

Glassdoor

4.0

Sanofi is a healthcare company that provides treatments and the protection of life-saving vaccines.

Founded in 1973

Paris, Ile-de-France, FRA

10,001+ employees

https://www.sanofi.com

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