Merck · 2 days ago

Senior Scientist, Discovery Oncology

South San Francisco, CA

Full-time

Hybrid

Senior Level

$125K/yr - $197K/yr

4+ years exp

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BiotechnologyHealth Care

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Comp. & Benefits

Insider Connection @Merck

Discover valuable connections within the company who might provide insights and potential referrals, giving your job application an inside edge.

Responsibilities

Identify and target steps in disease mechanisms or pathways for potential inhibition or enhancement.

Isolate compounds effective against disease targets.

Collaborate in a cross-functional team to discover medical breakthroughs.

Support research projects for developing novel cancer therapies with strong cell-based experimental skills.

Work independently and excel in a highly collaborative environment.

Qualification

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Cell CultureCell-Based AssaysExperimental DesignData AnalysisStatistical ConceptsFlow CytometryMolecular BiologyBiochemistryWestern BlottingImmunofluorescent StainingEnzyme-Linked Immunosorbent AssayMolecular CloningGraphPad PrismFlowJoPublication RecordProblem-SolvingCommunicationTeam PlayerSelf-MotivatedPositive AttitudeIntegrityHandling human tissues

Required

Bachelor's (with 7+ years), Master's (with 4+ years) or Ph.D. in Cancer Biology, Cell Biology, Pharmacology, Immunology or related discipline and relevant years of experience

Experience supporting research projects, demonstrated by publications in academia or industry

Prior work with cell culture and cell-based assays, for example, drug treatment, measurement of cell viability, imaging, and quantification of cytokine production in multi-well plate settings

Experience designing and executing cell biology, molecular biology and biochemistry experiments, such as multi-parameter flow cytometry, cell line engineering (e.g., CRISPR, RNAi, target over-expression), western blotting, immunofluorescent staining, enzyme-linked immunosorbent assay, molecular cloning, etc.

Data analysis skills with a sound comprehension of statistical concepts (ex: analytic methods in GraphPad Prism and FlowJo)

Strong communication and presentation skills

Self-motivated and data-driven team player with integrity and a positive attitude