49 applicants

Company

Original Job Post

AbbVie · 3 days ago

Scientist I - Protein Science

Irvine, CA

Full-time

Onsite

Entry, Mid Level

2+ years exp

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BiotechnologyHealth Care

H1B Sponsorship

Comp. & Benefits

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Responsibilities

Recombinant expression and purification of early-stage discovery proteins.

Conceiving, designing, and executing the engineering of innovative biotherapeutics.

Proposing, designing, and executing cloning strategies.

Leveraging expertise in molecular biology and protein engineering techniques.

Characterizing proteins using various techniques like SDS-PAGE, native PAGE, ELISA, Western Blot.

Interacting with cross-functional and matrixed teams to collaborate on discovery projects.

Qualification

Find out how your skills align with this job's requirements. If anything seems off, you can easily click on the tags to select or unselect skills to reflect your actual expertise.

Molecular BiologyProtein EngineeringBiochemistryCloningProtein ExpressionProtein PurificationBioinformaticsSequence AnalysisBLASTSnapGeneGeneious PrimeModeling SoftwarePymolRecombinant Protein ExpressionAKTA FPLCProtein Separation TechniquesIMACSECIon ExchangeHICTagless Protein PurificationRecord KeepingExperimental DesignData AnalysisTechnical ReportsLiterature ReviewProblem-SolvingAttention to DetailCommunicationAutonomous

Required

Bachelor’s Degree + 5 or more years of experience OR a Master’s degree and 2 or more years of experience

Thorough theoretical and practical understanding of Molecular Biology, Protein Engineering, Biochemistry and/or related discipline with a focus in cloning, heterologous protein expression, protein purification and characterization

Proven experience in molecular biology and plasmid construction (PCR, site-directed mutagenesis, restriction enzyme-based cloning, ligase independent cloning (LIC)), Sanger DNA Sequencing

Solid knowledge in bioinformatics and sequence design/analysis software (e.g., BLAST, SnapGene, Geneious Prime)

Familiarity with modeling software (Pymol) and its application to protein design

Proficient in recombinant protein expression in heterologous hosts (E. coli, baculovirus, mammalian)

Skilled with AKTA FPLC purification systems

Demonstrated proficiency in protein separation techniques (IMAC, SEC, ion exchange, HIC)

Experience with tagless protein purification

Meticulous attention to detail and diligence in record keeping

Excellent oral and written communication skills required as is experience with documentation of experimental plans, analyzing data and generating high quality technical reports

Highly autonomous and productive in performing laboratory research or method development, requiring only minimal direction from or interaction with supervisor

Understand relevant scientific literature and apply theoretical framework to solving problems within scientific discipline in a timely manner

Preferred

Experience with Molecular Biology techniques, knowledge of protein engineering strategies and protein characterization techniques including SDS-PAGE, native PAGE, ELISA and Western blot are desirable

Benefits

Paid time off (vacation, holidays, sick)

Medical/dental/vision insurance

401(k)

Short-term incentive programs

Company

AbbVie

Glassdoor

3.9

AbbVie is a pharmaceutical company that discovers, develops, and markets medicines.

Founded in 2013

North Chicago, Illinois, USA

10,001+ employees

http://www.abbvie.com

H1B Sponsorship

AbbVie has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Trends of Total Sponsorships

2023 (155)

2022 (299)

2021 (194)

2020 (197)