30 applicants

Company

Original Job Post

Novartis · 3 days ago

Principal Scientist - Neuroscience

Cambridge, MA

Full-time

Onsite

Senior Level

$124K/yr - $186K/yr

7+ years exp

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Responsibilities

Support Neuroscience discovery programs based on high-quality experimental data that incorporates single neuron, synaptic and/or circuit approaches.

Formulate and/or leads novel projects with multidisciplinary teams, and/or enables matrix collaboration on projects/technologies to achieve creative results for impact on Neuroscience goals.

Effectively execute experiments in the lab and intellectually driving projects forward.

Develop and implement assays to assess synaptic structure, function and/or plasticity in disease models, considering interactions with astrocytes / microglia.

Evaluate the impact of therapeutic candidates in neural/synaptic/circuit function.

Play a role in identifying tractable therapeutic targets and initiating exploratory efforts to modulate them.

Provide expert input into understanding the genetics and biology of neurodegenerative and / or neurogenetic disorders.

Establish priorities and target dates to enable data-driven advancements in portfolio and/or platform projects.

Qualification

Find out how your skills align with this job's requirements. If anything seems off, you can easily click on the tags to select or unselect skills to reflect your actual expertise.

Pharmaceutical experience vitro/ex vivo/in vivo model systemsElectrophysiological techniquesMolecular approachesAnatomical approachesNeurodegeneration knowledgeNeurogenetic disorders knowledgeDisease progression mechanismsMatrix structure collaborationTeam managementPortfolio mindsetProblem-solvingCommunicationTeamwork

Required

MS with 7+ years of pharmaceutical/biotech experience.

Hands-on expertise in complex in vitro / ex vivo / in vivo model systems and circuit level analysis that leverages electrophysiological, molecular and/or anatomical approaches.

Deep biological knowledge of neurodegeneration and/or neurogenetic disorders, including mechanisms of disease progression and core drivers of disease.

Aptitude to work in a matrix structure and demonstrable experience collaborating / managing multidisciplinary teams directly and/or by influence.

Ability to communicate effectively and present complex and/or new ideas with clarity and simplicity.

A team-first and portfolio mindset are qualities that we strongly seek and value.

Preferred

PhD in Neuroscience or related field, with 3+ years of pharmaceutical/biotech experience

Benefits

401(k) eligibility

Various paid time off benefits, such as vacation, sick time, and parental leave

Company

Novartis

Glassdoor

3.9

Novartis is a healthcare company that provides solutions to address the evolving needs of patients worldwide.

Founded in 1996

Basel, Basel-Stadt, CHE

10,001+ employees

https://www.novartis.com

H1B Sponsorship

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