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Company

Original Job Post

BioSpace · 2 days ago

Scientist I, Purification Development

South San Francisco, CA

Full-time

Onsite

Entry, Mid Level

2+ years exp

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Comp. & Benefits

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Responsibilities

Develop, optimize, and scale-up purification processes

Support transfer processes to GMP manufacturing site for clinical material production

Work efficiently, collaboratively, and cross-functionally toward project timelines and goals

Work with contract labs and carry out viral clearance studies

Write technical reports

Author and deliver technical presentations

Qualification

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Protein purificationChromatographyFiltration operationsExperimental designBiochemistryBioprocess engineeringAKTA chromatographic instrumentsScientific writingMicrosoft Office proficiencyTechnical report writingCollaborationAttention to detailAnalytical skillsPlanningVerbal communicationAntibody PurificationResin ChromatographyAffinity ChromatographyCEX ChromatographyAEX ChromatographyMMC ChromatographyDepth FiltrationVirus FiltrationMembrane ChromatographyTFF OperationsMonoclonal Antibody PurificationGMP ExperiencePilot Scale ExperienceLaboratory Scale ExperienceAnalytical Techniques

Required

Bachelors Degree or equivalent education and typically 5 years of experience and MS or equivalent education and typically 2 years of experience

Must have protein purification experience including chromatography separations and filtration operations

Must have excellent attention to detail and ability to keep detailed written records

Demonstrated ability to independently design, execute and interpret critical experiments to answer scientific questions

Demonstrated ability to learn, understand and master new experimental techniques

Able to work collaboratively within and outside of the group

Able to author technical reports and presentations

Has understanding of biochemistry and bioprocess engineering concepts

Has strong planning and analytical skills

Experience with AKTA chromatographic instruments (such as AKTA Avant, AKTA Purifier, AKTA Pure or similar)

Demonstrated scientific writing skills and strong verbal communication skills including scientific data presentations

Has proficiency with Microsoft Office software, ability to learn new software applications

Preferred

Has hands on experience with executing antibody or antibody-like molecule purification techniques including resin chromatography (affinity, CEX, AEX, MMC), depth filtration, virus filtration, membrane chromatography, and TFF operations.

Has hands on experience with monoclonal antibody or antibody-like molecule purification at GMP, pilot and/or laboratory scale

Understanding of analytical techniques, such as HPLC, LAL, and ELISA

Has hands on experience with high-throughput technologies and automation