myGwork - LGBTQ+ Business Community · 2 days ago

Engineer/Associate Scientist, Oligonucleotide Purification Development

Cambridge, MA

Full-time

Onsite

Entry, Mid Level

2+ years exp

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Responsibilities

Develop and characterize purification processes for a pipeline of new oligonucleotides drug therapies utilizing chromatography and ultrafiltration.

Investigate new purification technologies to enhance purity, robustness, and productivity of existing processes.

Collaborate cross-functionally to improve process understanding and manage team activities.

Document laboratory work, lead pilot scale activities, and participate in technology transfer processes.

Act as a subject matter expert on purification processes and facilitate interactions within the organization.

Qualification

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Project PlanningTechnical ProficiencyInnovative TechnologiesLab ExperienceColumn ChromatographyUF/DFProtein AnalysisDNA/RNA AnalysisHPLCUV/Vis SpectroscopyAKTA Purification SystemsUnicorn SoftwareStatistical DesignDoEStatistical AnalysisProblem-SolvingCreativityCommunicationTeamworkMotivated

Required

Bachelor’s degree in Biochemistry, Chemical Engineering, or related life science field with 2-4 years industry experience (or master’s degree with 0-2 years of industry experience) is required.

Proven record of successfully planning and executing projects and experiments

Demonstrated technical proficiency and creativity in developing innovative technologies/approaches in purification.

Lab experience in purification of proteins and/or DNA/RNA using column chromatography (e.g., Ion exchange, Hydrophobic Interaction, and/or Reversed phase) and UF/DF.

Some hands-on experience in analysis of proteins or DNA/RNA, preferably using both HPLC and UV/Vis spectroscopy. Experience using AKTA purification systems and Unicorn software and use of statistical design (DoE) are a plus. Experience in statistical analysis is also a plus.

Motivated to work and communicate both individually and within teams