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Arc Institute · 2 days ago

Senior Scientist, Bioinformatics

Palo Alto, CA

Full-time

Onsite

Senior Level

$152K/yr - $190K/yr

5+ years exp

Arc Institute is a new scientific institution conducting basic science and technology development to understand and treat complex human diseases. They are seeking a Senior Scientist to join the Bioinformatics team to advance the Virtual Cell Initiative, creating predictive models of cellular states and identifying therapeutic targets for diseases.

BiotechnologyNon ProfitTraining

H1B Sponsor Likely

Responsibilities

Lead the efforts to design and implement state-of-the-art analysis pipelines for various high-throughput projects using best software engineering practices

Manage analysis projects for large-scale sequencing datasets (single-cell RNA-seq, epigenomics, multi-omics, Perturb-seq, spatial transcriptomics)

Develop novel machine learning algorithms to get biological insights from the multifaceted genomic datasets

Lead computational side in the cross-functional teams tasked with developing novel genomic technologies

Mentor junior scientists in developing computational methods and utilizing bioinformatics tools and pipelines

Qualification

Computational GenomicsBioinformaticsMachine LearningNext-Generation SequencingSingle-Cell Multi-OmicsPythonGit/GitHubLinuxStatistical SkillsCuriosityProject ManagementCollaborationOrganizational SkillsCreativity

Required

Ph.D. in Bioinformatics, Computational Biology, Computer Science, or related quantitative field, with 5+ years of industry/academia experience

Hands-on experience analyzing high-throughput sequencing datasets, especially on single-cell omics data (bulk and single-cell RNA-seq and ATAC-seq, Perturb-seq, etc.)

High competency with Python, git/GitHub, and Linux

Demonstrated ability to collaborate with wet-lab scientists

Strong statistical, mathematical, and analytical skills

Preferred

Experience analyzing spatial transcriptomics, optical pooled screens, cell painting, and other imaging technologies

Familiarity with CRISPR screens technology and analyses

Scientific background in neuroscience or cancer biology

Experience with Nextflow pipelines

Familiarity with cloud computing

Benefits

Annual discretionary bonus

Company

Arc Institute

Arc Institute is a biomedical science and research technology company.

Founded in 2021

Palo Alto, California, USA

51-200 employees

https://arcinstitute.org

H1B Sponsorship

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