Takeda · 10 hours ago
Staff Engineer, Modeling
Boston, MA
Full-time
Onsite
Senior Level, Lead/Staff
$112K/yr - $176K/yr
5+ years expTakeda is a company focused on developing robust and cost-effective processes for the manufacture of new small molecule pharmaceuticals. The Staff Engineer – Process Modeling will join a dynamic team to tackle challenges in chemical reaction engineering and enhance process understanding through mathematical modeling and data-rich experimentation.
BiotechnologyHealth CareManufacturingMedicalPharmaceutical
Responsibilities
Contributes to the design, development, optimization, and scale-up of manufacturing processes for synthetic molecule drug substances using process modeling and simulation principles
Utilizes advanced process modeling tools and digital twin functionalities, implementing model-based design of experiments for process characterization and risk assessment
Develops experimental designs and workflows for model development, validation, and verification
Collaborates with cross-functional and external partners to develop and deploy digital twins of unit operations
Partners with Automation, Manufacturing, Process Engineers, and PAT experts to develop modeling and simulation (M&S) solutions that can be deployed across the global organization for in-silico process design, development, and optimization
Recommends, justifies and implements in silico tools and an "in-silico first” approach to process development
Responsible for authoring relevant sections of regulatory documents, validation plans, reports and peer reviewed manuscripts
Proactively analyze technical issues and coordinate potential resolutions with project team members based on model and simulation predictions
Qualification
Required
Bachelor's degree in Chemical Engineering or a related pharmaceutical science with 5+ years of relevant industry experience
Master's degree in Chemical Engineering or a related pharmaceutical science with 3+ years of relevant industry experience
Ph.D. in Chemical Engineering or a related pharmaceutical science with 0+ years of relevant industry experience
Strong knowledge and understanding of chemical reaction engineering and catalysis, with proven ability to demonstrate skills in these fields
Strong knowledge and understanding of transport phenomena and thermodynamics
Experience with commercially available reaction kinetic modeling software such as ReactionLab, Dynochem, gPROMS and COMSOL
Experience with commercially available software for computational fluid dynamics (CFD) modeling such as Ansys, Star CCM+, MStar CFD
Proficient in communicating and data collection from systems such as sensors, controllers, and industrial systems
Experience with Matlab, Python, R, SQL, and good coding practices
Analytical and Problem Solving Skills - Able to troubleshoot critical issues or problems, and determine causes and possible solutions
Teamwork -- Ability to work well in highly cross functional team environment and across global line functions
Communication Skills - Able to express one's self clearly and concisely within team; documents issues and/or concerns concisely with colleagues; adjusts communication style as appropriate for the audience; timely and effectively communicates issues to supervisor; technical writing skills to support authorship of internal technical documents
Organization – Exercises good time management and prioritization skills and is able to successfully manage multiple tasks simultaneously
Knowledge Sharing - Ability to capture organizational knowledge; improve solutions, processes, and deliverables through use of information; improve information capital by contributing experience, theories, deliverables, and models for others to use
Resource Management - Ability to manage one's time within individual, departmental, and corporate goals and timelines; management of internal and external resources (vendors)
External Involvement – Demonstrated involvement in professional community evidenced by presentation of scientific posters or lectures at professional conferences or events
Technical - Subject matter expertise and knowledge of applicable process modeling and simulation tools
Preferred
Experience with common statistical methods, basic data science principles, and AI/ML methodologies
Hands-on experience in wet lab process development
Experience in multivariate analysis and Principal Component Analysis (PCA)
Understanding of synthetic molecule process development activities
Understanding of current Good Manufacturing Practices (cGMP)
Benefits
Medical, dental, vision insurance
401(k) plan and company match
Short-term and long-term disability coverage
Basic life insurance
Tuition reimbursement program
Paid volunteer time off
Company holidays
Well-being benefits
Up to 80 hours of sick time
Up to 120 hours of paid vacation
Company
Takeda
Takeda is a biopharmaceutical company that researches and develops pharmaceutical drugs.
10001+ employees
H1B Sponsorship
Takeda has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (45)
2024 (39)
2023 (38)
2022 (34)
2021 (44)
2020 (18)
Funding
Current Stage
Public CompanyTotal Funding
$2.46B2025-06-27Post Ipo Debt· $2.4B
2016-09-01Grant· $19.8M
2016-05-08Grant· $38M
Leadership Team
Christophe Weber
President and CEO
Schuyler Fairfield
Senior Vice President, Global Head of Supply Chain
Recent News
2025-12-30
Company data provided by crunchbase