Matterworks · 5 months ago
Principal Machine Learning Scientist
United States
Full-time
Remote
Lead/Staff
10+ years expMatterworks is building AI tools to extract insights from biological data, focusing on therapeutic discovery and development. As a Principal Machine Learning Scientist, you will lead the technical vision and strategy for deep learning architecture, guiding the scientific direction and mentoring a team of scientists.
Artificial Intelligence (AI)BiotechnologyMedicalPharmaceutical
Responsibilities
Architectural Vision and Strategy: Define and drive the long-term vision for our core deep learning architecture. Make critical decisions on the foundational design of our neural networks to ensure they are scalable, robust, and optimized for interpreting mass spectrometry data
Foundational Model Development: Lead the conceptualization, design, and implementation of innovative deep learning models. Your work will involve creating novel network architectures and algorithms tailored to scientific discovery
Scientific Leadership: Provide intellectual leadership to the machine learning team and the broader company. Stay at the forefront of academic and industry advancements in deep learning, particularly as they apply to chemistry and biology, and guide the team in applying cutting-edge techniques
Cross-Functional Collaboration: Work closely with leadership in engineering, product, and scientific discovery to align machine learning initiatives with company-wide goals
Mentorship and Guidance: Mentor and develop our team of machine learning scientists, fostering a culture of technical excellence, creativity, and rigorous scientific inquiry
Qualification
Required
Ph.D. in a quantitative field such as Computer Science, Chemistry, Physics, or a related discipline, or equivalent research experience
10+ years of experience in machine learning, with a significant focus on architecting novel deep learning systems
Demonstrated experience in leading the architectural design of complex deep learning systems. This should be evident through publications, patents, or a portfolio of shipped products
Proficiency with common scientific data formats (e.g., HDF5, mzML, zarr)
Preferred
Expertise or strong familiarity with machine learning for spectral analysis, molecular structure prediction, or novel molecular representation learning is highly preferred
A strong publication record in top-tier machine learning or scientific journals (e.g., NeurIPS, ICML, Nature, Science) is highly desirable
Benefits
Health & dental
Vision
Long- and short-term disability
Life insurance
401k with company match
Flexible work & unlimited time away policy
Commuter benefits and parking
Regular team meals and outings
Company support for continued education/coursework and conference participation
Company
Matterworks
Matterworks is a biotech startup that combines metabolomics with AI to simulate the metabolic environment.
11-50 employees
H1B Sponsorship
Matterworks has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (1)
Funding
Current Stage
Early StageTotal Funding
$13.75MKey Investors
Germin8 Ventures
2025-06-03Series A
2023-08-14Seed· $7.5M
2023-01-01Convertible Note
Leadership Team
Jack (J.M.) Geremia, PhD
Chief Executive Officer
Recent News
globallegalchronicle.com
2025-07-05
2025-06-11
2025-06-11
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