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Simons Foundation · 2 weeks ago

Senior Software Engineer & Project Lead, Biology

New York, NY

Full-time

Onsite

Senior Level, Lead/Staff

$190K/yr - $235K/yr

10+ years exp

Simons Foundation is seeking an experienced software engineer to be the Project Lead for HumanBase, a web-based platform supporting biomedical researchers. The role involves leading technical direction, mentoring engineers, and collaborating with researchers to develop software tools that advance the study of human genomics and disease.

AssociationBiotechnologyEducationNon Profit

Comp. & Benefits

H1B Sponsor Likely

Hiring Manager

Kelly Hoey

Responsibilities

Serve as technical lead for HumanBase, guiding the design, architecture, and implementation of new features and major infrastructure upgrades

Lead and mentor a team of full stack software engineers, ensuring high-quality code, efficient workflows, and continuous professional development

Plan, develop, and optimize scalable genomics data processing pipelines

Integrate machine learning methods into production pipelines to analyze heterogeneous biological datasets

Establish and enforce software engineering best practices, including coding standards, version control, documentation, testing, and deployment workflows

Collaborate cross-functionally with computational biologists, data scientists, and external partners to align engineering efforts with scientific goals

Stay current with emerging technologies in cloud infrastructure, bioinformatics, and scientific computing and assess their relevance for HumanBase

Perform additional duties or projects as assigned

Qualification

PythonFull stack developmentBioinformatics experienceTechnical leadershipSoftware development lifecycleData processing pipelinesWeb-based applicationsCuriosity about scienceDriveCommunicationMentorship abilitiesOwnership

Required

B.S. in Computer Science, Software Engineering, or a related technical field

At least 10 years of professional software experience in software engineering, including leading teams and direct involvement in the planning, design, and development of software

Experience collaborating daily with other key team members of different technical and scientific backgrounds

Proficiency in full stack software development

Extensive experience in Python, including developing data pipelines and software libraries

Demonstrated experience with the full software development lifecycle (SDLC), including testing, CI/CD, version control, and deployment

Experience building and maintaining web-based interfaces and applications

Background in computational biology, bioinformatics, or a related field, with experience developing software in support of biological research

Experience working with large, heterogeneous biological datasets—ideally in genomics or biomedical contexts

Effective technical leadership and mentorship abilities

Excellent communication skills, especially when working across disciplinary boundaries

Deep curiosity about science and a passion for building tools that empower scientific discovery

Strong sense of ownership and drive for continuous improvement

Benefits

An outstanding benefits package

Company

Simons Foundation

Simons Foundation is a private foundation funding research in mathematics and the basic sciences.

Founded in 1994

New York, New York, USA

201-500 employees

https://www.simonsfoundation.org

H1B Sponsorship

Simons Foundation has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Represents job field similar to this job

Trends of Total Sponsorships

2025 (38)

2024 (30)

2023 (34)

2022 (27)

2021 (16)

2020 (18)