The University of Georgia ยท 5 months ago
Post Doctoral Research Associate
The University of Georgia, Georgia's oldest and most comprehensive institution of higher education, is seeking a Post Doctoral Research Associate. This role involves designing and developing recombinant DNA constructs, optimizing protein purification protocols, and characterizing glycosylation enzymes, while also supervising and training research staff.
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Responsibilities
Design of new recombinant DNA constructs within the Moremen lab, generation of recombinant expression constructs, verification by DNA sequencing, and protein expression of a collection of glycosylation enzymes for biochemical and structural characterization
Establishing and optimizing strategies and protocols for protein purification and troubleshooting the isolation of numerous recombinant products including processing in preparation for enzymatic and structural studies
Detailed enzymatic characterization of recombinant glycosylation enzymes including isolation of wild type and mutant enzyme forms and full characterization of kinetic parameters with multiple enzyme substrates
Organize projects in consultation with researchers at remote sites for collaborative projects including preparation of samples, data and reports for these collaborations
Training and supervision of Research Professionals, Research Technicians, and undergraduate researchers in their duties on generation of recombinant constructs, protein purification, and characterization
Interaction with structural biology groups for preparation of samples for enzymatic glycan synthesis, NMR analysis, and crystallization
Qualification
Required
A PhD in biochemistry or molecular biology is expected
Experience in molecular biology, biochemistry, computational biology, protein expression, purification, and general laboratory methods are required
Detailed capabilities to carry out molecular biology and biochemistry protocols
Ability to run all aspects of the protein expression platform
Coordinating and supervising numerous concurrent projects from initiation to completion
Well trained in molecular biology, protein biochemistry, enzymology, and computational analysis of modeled protein structure
Preferred
Preferred expertise in glycoscience and large-scale protein expression in bacteria and mammalian cell culture
Company
The University of Georgia
The University of Georgia, a land-grant and sea-grant university with state-wide commitments and responsibilities, is the state's flagship institution of higher education.
Funding
Current Stage
Late StageLeadership Team
Recent News
Alfred P. Sloan Foundation
2023-10-27
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