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Kardigan · 1 day ago

Postdoc / Visiting Scientist – Bioengineering CV Research models

South San Francisco, CA

Full-time

Onsite

Mid, Senior Level

$77K/yr - $101K/yr

Kardigan is a heart health company focused on making cardiovascular disease preventable and curable. They are seeking a postdoc/visiting scientist with a bioengineering background to develop in vitro models for studying cardiovascular diseases, ultimately contributing to the next generation of therapies and training future translational scientists.

Artificial Intelligence (AI)BiopharmaHealth CareMedical

H1B Sponsor Likely

Responsibilities

Design, fabricate, and optimize 3D EHT constructs using atrial, ventricular myocardium, and aortic valve leaflets

Integrate various cell types (e.g., iPSC-derived cardiomyocytes, fibroblasts, valvular cells) into tissue constructs and in vitro models

Ensure tissue viability, maturation, and functional integrity over time

Perform in vitro functional measurements of contractility as well as tissue compliance/ stiffness

Analyze differences between healthy vs. disease models to understand pathophysiology and disease mechanism

Conduct immunohistochemistry, confocal microscopy, qPCR, and Western blotting to evaluate structural and functional markers

Conduct in vitro assay screening of Kardigan compounds

Perform quantitative analysis of biomechanical and molecular data, create reports and communicate findings to company-wide meetings

The project must lead to at least one scientific publication

Qualification

Bioengineering3D cardiac tissue modelsBiomaterialsIPSC cultureTissue engineeringPublication recordProblem-solvingCommunication

Required

A PhD in Biomedical Engineering, Cardiac Physiology, Bioengineering, Cell Biology or related field

Strong background in Biomaterials

Research experience with engineered heart tissue (EHT) or 3D cardiac tissue models

Expertise in biomaterials, 3D printing, hydrogels and/or scaffold-based approaches

Strong publication record in tissue engineering, cardiovascular research and/or mechanobiology

Ability to work independently as well as in cross functional teams

High energy, with a passion for fundamental disease understanding, quality drug development, and entrepreneurial spirit

Strong problem-solving capacity - enjoys complex challenges and has the accountability to deliver on ambitious, but realistic, business, and scientific goals

Excellent communication skills – ability to communicate science clearly and effectively to a broad range of audiences including non-specialists

Preferred

Familiarity with cell culture including induced pluripotent stem cell (iPSC) culture, cardiac differentiation and primary isolation and culture protocols

Company

Kardigan

Kardigan develops personalized medicines using AI and data to target and treat the root causes of cardiovascular diseases.

Founded in 2023

South San Francisco, California, USA

51-200 employees

https://www.kardigan.bio

H1B Sponsorship

Kardigan has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Represents job field similar to this job

Trends of Total Sponsorships

2025 (1)