Mount Sinai Health System · 4 months ago
Bioinformatician II - Psychiatry
New York, NY
Full-time
Onsite
Entry, Mid Level
$66K/yr - $100K/yr
2+ years expMount Sinai Health System is seeking a proactive and detail-oriented Bioinformatician II to join their Center for Disease Neurogenomics. The role involves supporting the analysis, infrastructure, and data stewardship of large-scale functional genomics datasets, focusing on omics data management and computational infrastructure maintenance.
Health CareHospitalMedical
Responsibilities
Assist in the preprocessing, demultiplexing, and quality control of single-cell and bulk sequencing data across multiple assays (RNA-seq, ATAC-seq, multiome)
Implement and maintain metadata infrastructure for tracking donor/sample provenance and cohort selection across projects using a relational database backend
Monitor and maintain local high-performance computing resources, including scripting of automated usage summaries, quota alerts, and issue tracking
Support data transfers, pipeline execution, and user coordination in hybrid cloud environments (e.g., CAVATICA, GCP)
Write and maintain robust, well-documented code (e.g., Snakemake, bash, R, Python) for processing and managing large-scale datasets
Respond to infrastructure incidents (e.g., disk quota overflows, data loss risks) and proactively implement safeguards
Contribute to documentation and training materials to enable team-wide system usage
Other related duties as assigned
Qualification
Required
M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered
2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.; with ≥3 years of experience preferred
Advanced knowledge of genetics and/or statistical analysis software and online resources. Experience in programming environments such as MatLab, R statistical package, BioConductor, Perl and C++
Proficiency in Python and R; working knowledge of SQL and Linux shell scripting
Experience processing large-scale omics data (RNA-seq, ATAC-seq, or WGS)
Experience using or developing Nextflow or Snakemake-based pipelines is a strong plus
Strong problem-solving skills, ability to prioritize, and attention to reproducibility and data integrity
Preferred
Demonstrated experience maintaining or developing data tracking systems or LIMS solutions
Familiarity with HPC environments and workload managers (e.g., LSF, SLURM)
Experience with cloud-based genomics analysis platforms such as CAVATICA, Verily Workbench, Google Cloud Platform (GCP), Amazon Web Services (AWS), or comparable environments
Experience with data privacy standards and compliance in biomedical datasets
Company
Mount Sinai Health System
Mount Sinai Health System delivers integrated medical care, research, and medical education through its network.
10001+ employees
H1B Sponsorship
Mount Sinai Health System has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (3)
2023 (26)
2022 (20)
2021 (6)
2020 (20)
Funding
Current Stage
Late StageTotal Funding
$41.9MKey Investors
National Institutes of HealthHearst Health Prize.Multiple Myeloma Research Foundation
2024-11-11Grant· $7M
2024-06-06Grant· $0.1M
2023-11-02Grant· $7M
Leadership Team
Vincent Tammaro
Executive Vice President and Chief Financial Officer
David Feinberg
Senior Vice President, Chief Marketing and Communications Officer
Recent News
Digital Journal
2026-01-08
Company data provided by crunchbase