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Convergent Research · 4 months ago

Computational Scientist - Single-Cell Algorithms

Watertown, MA

Full-time

Hybrid

Mid Level

Convergent Research is a non-profit research institute focused on advancing protein analysis technology. They are seeking a Computational Scientist to lead the design and development of computational analysis pipelines for mass spectrometry proteomics data, specifically related to Alzheimer’s Disease and Immuno-Proteome Aging projects.

BiotechnologyLife ScienceNon Profit

H1B Sponsor Likely

Responsibilities

Develop and adapt pre-processing algorithms for mitigation of data collection artifacts

Work with biological project leads to define hypotheses and apply appropriate statistical framework

Design and develop optimized analysis pipelines for large ‘omics datasets

Perform deep and detailed analyses for data-intensive experiments with team members and communicate interpretable results

Hands-on development of interactive tools for data interpretation of high throughput proteomics datasets for other team members using RShiny, Python, D3, or other tools

Curate large-scale datasets for internal and external usage

Mentor scientists and research associates

Prepare internal reports and manuscripts as well as present results at internal or external scientific meetings as appropriate

Demonstrate a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others

Other duties as assigned

Qualification

Single-cell 'omics experienceMass spectrometry dataR proficiencyPython proficiencyStatistical analysisMachine learning algorithmsData set alignmentModel validationMentoringCommunication skillsTeam collaboration

Required

Advanced degree in Statistics, Mathematics, Bioengineering, Computer Science, or other computational science

Demonstrable professional or PhD experience working with professional biologists on single cell ‘omics questions

Strong understanding of generalized linear models and nonparametric regression, hypothesis testing, optimization, dimension reduction techniques, and machine learning algorithms

Advanced proficiency in R and/or Python

Demonstrable experience with data set alignment, batch correction, cell type assignment, differential abundance testing, and gene ontology mapping

Experience handling terabyte-scale biological data

Demonstrable experience with model validation: cross validation, bootstrapping, posterior predictive, or simulation-based model checking

Preferred

Experience with proteomics spectral library prediction

Must have single cell 'omics experience OR experience working with mass spectrometry data

Benefits

Excellent medical, dental, and vision insurance with many $0 premium options for you and your family with several national and regional providers. Most employees have more than 20 plan options to choose from.

Company-paid group life, AD&D, long- and short-term disability insurance

15 days PTO + 10 sick days per year

18 company holidays + your birthday off

$5,000 per year educational reimbursement

Up to 16 weeks paid parental leave

Company

Convergent Research

Convergent Research is a focused research organization for conducting non-profit science projects and research.

Founded in 2021

Palo Alto, California, USA

51-200 employees

https://www.convergentresearch.org/

H1B Sponsorship

Convergent Research has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Represents job field similar to this job

Trends of Total Sponsorships

2023 (11)

2022 (5)