High-Performance Computing (HPC) Systems Engineer jobs in United States
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Axle · 4 months ago

High-Performance Computing (HPC) Systems Engineer

Axle is a bioscience and information technology company focused on advancements in translational research and biomedical informatics. They are seeking a High-Performance Computing (HPC) Systems Engineer to support the Scientific Computing and Informatics team at the National Center for Advancing Translational Sciences (NCATS), where the role involves designing, optimizing, and maintaining HPC and cloud-based infrastructures for biomedical research.

BiotechnologyHealth CareInformation TechnologySoftware
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H1B Sponsor Likelynote

Responsibilities

Design, configure, and maintain scalable HPC clusters for optimal performance
Support documentation and ATO (Authority to Operate) processes
Ensure infrastructure design compliance with federal security standards and best practices
Implement monitoring tools such as XDMoD for transparency and user reporting
Integrate platforms such as JupyterHub and job schedulers (e.g., Slurm) for improved interactivity
Develop and manage AWS-based infrastructure using Terraform, Packer, and Ansible
Automate deployment workflows to streamline provisioning, updates, and scaling
Manage systems involved in AWS Secure Cloud Bridging (SCB) and STRIDES initiatives
Implement CIS benchmark-aligned system hardening using OpenSCAP
Administer optimized compute images (CPU/GPU) for scientific workflows
Leverage tools such as OpenHPC, Warewulf, and Ansible for environment management
Lead and coordinate quarterly patch cycles
Partner with researchers and external stakeholders on critical projects
Facilitate solution transitions to other NIH centers and collaborators
Contribute to publications and team objectives through deep technical engagement

Qualification

HPC architectureAWS infrastructureCybersecurity in HPCScientific software developmentHigh-speed networkingProgramming PythonLinux administrationMonitoring toolsMultitasking skillsCommunication

Required

Federal ATO processes experience required
HPC architecture and performance optimization is required
Scientific software development and deployment
High-speed network and parallel file system architecture
Troubleshooting, diagnostics, and technical support
Strong communication and multitasking skills
Programming & Scripting: Languages - Pascal, BASIC, Delphi, Visual Basic, C, C++
Scripting - Bash, Perl, Python, Ruby, PEAR, Tcl
Systems & Network Administration: Linux – RHEL/CentOS, SUSE, Debian, Ubuntu
Windows – 95–10; NT–Server 2016
Networking – Active Directory, TCP/IP v4/v6, DHCP, DNS, WINS
Legacy – NOVELL 3.1–5, VPN, Citrix, Terminal Services
Monitoring & Management Tools: Nagios, Ganglia, HP BAC, Precise i3
SGI SMC, HP PCM, Bright Cluster Manager (incl. Data Analytics)
Infrastructure & Automation: Puppet, Cobbler, Ansible, Chef
Red Hat Satellite, Kickstart, RPM optimization
File Systems & Archiving: Panasas (DirectFlow/panfs), DDN (GPFS), SGI DMF, StorHouse/RFS (Filetek)
HPC Tools & Job Scheduling: MOAB/MAUI, Torque, PBS Pro, Windows HPC Scheduler
Visualization & Remote Access: Nice DCV, EnginFrame, VNC, OpenText Exceed OnDemand, Web Remote Desktop
Containerization & GPU: Docker, Kubernetes, Kubeflow, NVIDIA DGX-1 GPU systems
Databases: SQL Server (2000–2008), MySQL, Zope
High-Speed Networking: Infiniband, Mellanox, OFED, Voltaire, Force10
Proven experience in: HPC architecture and performance tuning
Cybersecurity in HPC/cloud environments
Infrastructure as Code (AWS, Terraform, Ansible, Packer)
Supporting scientific workflows in research environments

Benefits

100% Medical, Dental & Vision Coverage for Employees
Paid Time Off and Paid Holidays
401K match up to 5%
Educational Benefits for Career Growth
Employee Referral Bonus
Flexible Spending Accounts:
Healthcare (FSA)
Parking Reimbursement Account (PRK)
Dependent Care Assistant Program (DCAP)
Transportation Reimbursement Account (TRN)

Company

Axle

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At Axle, we are driven by the mission to accelerate discovery and enhance organizational outcomes by revolutionizing operations with our innovative solutions.

H1B Sponsorship

Axle has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (37)
2024 (40)
2023 (61)
2022 (30)
2021 (19)
2020 (38)

Funding

Current Stage
Late Stage

Leadership Team

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Gary Mays
Chief Operating Officer
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Company data provided by crunchbase