St. Jude Children's Research Hospital · 4 months ago
Scientist - Protein and Biologics Screening Core (Host-Microbe Interactions)
St. Jude Children's Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. They are seeking a skilled Scientist for the Protein and Biologics Screening Core, focusing on antibody discovery to treat unmet pediatric diseases.
BiotechnologyCharityHealth CareHealth DiagnosticsHospitalMedicalNon Profit
Responsibilities
Design and execute antibody discovery campaigns from immunization to lead discovery
Utilize immunization, hybridoma/B-cell screening to drive binder discovery
Perform high throughput sorting to isolate specific B cell populations
Analyze and compare BCR sequences and immune repertoires
Serve as project leads for antibody discovery at St Jude
Strive for innovation and bring latest technologies to Biologics core
Maintain accurate and timely ELN data for discovery campaigns
Coordinate external discovery activities
Mentoring and help promote an inclusive work culture
Qualification
Required
Bachelor's degree in relevant scientific area is required
Eight (8) years of relevant work experience is required
Six (6) years of relevant work experience is required with a Master's degree
Three (3) years of relevant post-degree work experience is required with a PhD
Experience in Antibody Discovery
Experience in Hybridoma fusion/B-cell culture
Preferred
A PhD or equivalent is preferred with demonstrated post PhD experience in industry or academia
Extensive knowledge of B-cell immunology and antibody development
The ability to design and execute in vivo studies to evaluate antibody efficacy
Demonstrated experience with single B-cell antibody discovery approaches
Prior experience with Beacon for mAb discovery would be a plus
Hands-on experience in B-cell sorting and screening through flow cytometry, ELISA and bio-layer interferometry
Experience with antibody-related bioinformatic/software packages
Experience in NGS library preparation and BCR repertoire analysis
Experience in high-throughput cloning of antibody variable domains, antibody expression and characterization techniques (SPR, BLI, epitope binning)
Benefits
Comprehensive healthcare
Tuition assistance for continued education
Exceptional work-life balance with ample paid time off
Opportunities to enhance your professional growth in terms of scientific skills, soft skills, and your career
Competitive salary
Generous relocation assistance
No state income tax
On-site gym
An employee pharmacy
Company
St. Jude Children's Research Hospital
St.
H1B Sponsorship
St. Jude Children's Research Hospital has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (370)
2024 (316)
2023 (309)
2022 (255)
2021 (251)
2020 (201)
Funding
Current Stage
Late StageTotal Funding
$62.4MKey Investors
Kia MotorsKBR Charity Golf TournamentHyundai Hope On Wheels
2025-05-12Grant· $1.5M
2024-10-28Grant
2024-08-28Grant· $0.4M
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