Howard Hughes Medical Institute (HHMI) · 4 months ago
Research Specialist – Metabolic Sensor Design
Janelia Research Campus
Full-time
Onsite
Mid Level
$70K/yr - $114K/yrHoward Hughes Medical Institute (HHMI) is a pioneering research center focused on fundamental questions in the life sciences. They are seeking a Research Specialist to contribute to the CombinAItorial Sensor Design project, which involves engineering genetically encoded fluorescent biosensors using advanced machine learning and optical screening techniques.
BiotechnologyClinical TrialsHealth CareMedicalMedical Device
Responsibilities
Plan, coordinate, and execute pooled optical screening experiments for biosensor libraries
Design and clone DNA libraries of protein variants
Perform and oversee cell culture, transfection, sample preparation, and assay execution
Operate and maintain fluorescence microscopy systems, including FLIM
Work closely with AI and data analysis teams to ensure data quality, data annotation, and data transfer
Optimize workflows to improve throughput, reproducibility, and data quality
May supervise and mentor a research technician, assisting in experimental execution
Maintain accurate records of experiments, results, and protocol modifications
Qualification
Required
Ph.D. in molecular biology, bioengineering, biophysics, or related field
Strong hands-on experience with mammalian cell culture and fluorescence microscopy
Demonstrated ability to design, troubleshoot, and optimize complex experimental workflows
Familiarity with high-throughput screening methods and/or in situ sequencing
Excellent organizational, problem-solving, and communication skills
Preferred
Experience with fluorescence lifetime imaging (FLIM) and image analysis pipelines
Background in protein engineering or biosensor development
Experience collaborating with computational or machine learning teams
Benefits
A competitive compensation package, with comprehensive health and welfare benefits.
A supportive team environment that promotes collaboration and knowledge sharing.
The opportunity to engage with world-class researchers, software engineers and AI/ML experts, contribute to impactful science, and be part of a dynamic community committed to advancing humanity’s understanding of fundamental scientific questions.
Amenities that enhance work-life balance such as on-site childcare, free gyms, available on-campus housing, social and dining spaces, and convenient shuttle bus service to Janelia from the Washington D.C. metro area.
Exceptional health benefits
Retirement plans
Time off
A range of recognition and wellness programs.
Company
Howard Hughes Medical Institute (HHMI)
Founded in 1953, HHMI invests in scientists at all career stages who make discoveries that advance human health and our fundamental understanding of biology.
Founded in 1953
1001-5000 employees
H1B Sponsorship
Howard Hughes Medical Institute (HHMI) has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (135)
2024 (133)
2023 (133)
2022 (160)
2021 (133)
2020 (127)
Funding
Current Stage
Late StageTotal Funding
$1MKey Investors
Salt Lake Community College
2017-08-31Grant· $1M
Leadership Team
Boyana Konforti
Director of Scientific Strategy & Development
Recent News
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