Madrigal Pharmaceuticals · 4 months ago
Senior Director, Agentic AI and Automation
Conshohocken, PA
Full-time
Onsite
Director/Executive
$256K/yr - $312K/yr
15+ years expMadrigal Pharmaceuticals is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH). They are seeking a Senior Director of Agentic AI and Automation to lead the vision and deployment of AI-enabled automations across various functions, enhancing operational efficiency within a regulated biotech environment.
BiopharmaBiotechnologyMedical DevicePharmaceutical
Responsibilities
Define and execute a multi‑year agentic AI & RPA roadmap converging hyperautomation, process‑mining, and LLM‑driven workflows
Operationalize an Agentic Automation Center of Excellence (CoE) governing standards, reusable assets, and ROI tracking
Partner with cross‑functional executives to prioritise high‑value automations across the business
Champion MCP and agent‑orchestration patterns for future‑proof integration
Architect modular multi‑agent systems powered by frontier LLMs and leading agent frameworks (LangChain family, AutoGen, CrewAI, etc.)
Design secure agent‑to‑agent (A2A) communication with shared memory, credential vaults, RBAC
Implement enterprise MCP engine and Agent Protocol standards enabling human–agent–bot collaboration
Standardise integration with vector stores and cloud MLOps platforms (Azure AI Search, Databricks, SageMaker, Vertex AI)
Build event‑driven, low‑code pipelines (n8n, Dify, Glean) to trigger agentic RPA tasks in real time
Implement observability and governance (Arcade.dev, AgentOps, Langfuse)
Establish robust testing harnesses and GxP‑compliant validation for every autonomous workflow
Leverage process‑ & task‑mining insights to auto‑generate automation backlogs and measure value
Lead a multi‑disciplinary squad of AI automation architects, prompt engineers, and product managers
Drive iterative product delivery using agile OKRs, rapid POCs, and continual KPI evaluation
Experiment with cutting‑edge agent research (ReWOO, SuperAGI, CAMEL) and open‑source Agentic RPA
Collaborate with open‑source communities, cloud partners, and leading vendors
Set standards for agent safety, ethical AI, and closed‑loop feedback
Forge deep partnerships with Enterprise Data, IT Infrastructure, and Cybersecurity teams
Qualification
Required
Advanced degree (Ph.D. preferred) in AI, Data Science, Computer Science, Applied Mathematics, Engineering, Physics, or related field
15+ years leading AI/ML or intelligent‑automation initiatives; 10+ years hands‑on with Python, SQL, R, MATLAB, PyTorch, Keras, Git
12+ years architecting ML/deep‑learning solutions incl. LLMs (GPT‑4, BERT, LLaMA, Dolly) and RAG pipelines
8+ years building web apps (Dash, Streamlit, Shiny) and advanced data products
8+ years implementing scalable AI/ML on platforms like Databricks or Dataiku, with strong AI/MLOps
Deep knowledge of cloud data platforms (AWS, Azure, GCP) and compliance (GxP, HIPAA, GDPR)
Strong theoretical foundation in ML/AI with contributions to papers and presentations
Exceptional written & verbal communication skills translating complex research to executives
Extensive leadership experience managing cross‑functional technology teams in regulated industries
Benefits
Equity
Flexible paid time off
Medical
Dental
Vision and life/disability insurance
401(k) offerings (i.e., traditional, Roth, and employer match)
Supplemental life insurance
Legal services
Mental health benefits through our Employee Assistance Program for employees and their family
Company
Madrigal Pharmaceuticals
Madrigal Pharmaceuticals is a biopharmaceutical company developing therapeutics for the treatment of cardiovascular-metabolic diseases.
501-1000 employees
H1B Sponsorship
Madrigal Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (1)
Funding
Current Stage
Public CompanyTotal Funding
$1.94BKey Investors
Blue OwlHercules Capital
2025-07-22Post Ipo Debt· $350M
2024-03-18Post Ipo Equity· $690M
2023-09-28Post Ipo Equity· $500M
Leadership Team
Mardi C. Dier
Chief Financial Officer
Carole Huntsman
Chief Commercial Officer (CCO)
Recent News
2026-01-19
Pharma Letter
2026-01-11
Company data provided by crunchbase