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MUSC Health · 4 months ago

UNIV - Research Specialist II - Department of Pharmacology and Immunology

Charleston

Full-time

Onsite

Entry Level

1+ years exp

The Medical University of South Carolina is seeking a Research Specialist II for proteomic biomarker studies. The role involves sample preparation, data analysis, and maintaining laboratory equipment while ensuring safety and compliance in the lab.

Health CareHospitalMedical

Responsibilities

Sample organization and preparation. Individual will be familiar with randomization approaches to pre-prep sample organization using clinical characteristics and sample preparation for mass spectrometry studies. Sample preparation will include automated enzymatic digestion, buffer preparation, application of antibody tags in a clean environment. Individual will be capable of reaching milestone achievements

Data analysis. Individual will collaborate with multiple labs for image data processing and data modeling by simulators. Individual be familiar with verification and validation procedures to ensure appropriate modeling

Individual will use a variety of programs such as Excel, GraphPad, ImageJ and SPSS, python and R to report data. Individual will also learn and be able to communicate new proteomic software for peptide clustering and proteomic reporting

High throughput assays

Training students or visiting scholars in laboratory workflows surrounding proteomics

Maintain laboratory equipment. Individual will include system suitability tests on equipment used in each part of the study and record findings, troubleshooting when necessary

Keeping the lab safe, clean and compliant by following PPE and MUSC guidelines for safety in the laboratory

Qualification

ProteomicsMass SpectrometryChromatographyData AnalysisHPLCTandem Mass SpectrometryPythonRExcelGraphPadImageJSPSSPost-Translational ModificationsIsotopic LabelingDIADDATrapped Ion MobilityOrbitrap

Required

A bachelor's degree in chemistry, biology, or other natural, life or health care science

One year work experience directly related to the assigned research area

Ability to perform job functions in an upright position

Ability to perform job functions in a seated position

Ability to perform job functions while walking/mobile

Ability to climb, using step stool

Ability to work in temperature extremes (32° F to 100° F) when required due to assignments in cold rooms and/or foreign countries

Ability to work in confined/cramped spaces

Ability to bend at the waist

Ability to twist at the waist

Ability to fully use both hands/arms

Ability to perform repetitive motions with hands/wrists/elbows and shoulders

Ability to fully use both legs

Ability to reach in all directions, stretch, bend, while moving items/materials from both sitting and standing positions

Ability to maintain good olfactory sensory function/distinction

Ability to lift materials up to 20 lbs., unassisted

Ability to lift and carry 4 liter waste material bottles a distance of 30 feet, unassisted

Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet, unassisted

Ability to lift file boxes, from floor level to counter tops, unassisted

Ability to push/ Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches, then down 20 inches into centrifuge drum, unassisted

Ability to lift 25 lbs. boxes, from floor level to maximum height of 72 inches, unassisted

Ability to push/pull file boxes from one location to another at floor level

Ability to maneuver heavy equipment on bench tops, 50 lbs. or greater, unassisted

Ability to perform gross motor functions with frequent fine motor movements

Ability to maintain 20/40 vision, corrected, in one eye or with both eyes

Ability to match or discriminate between colors, normally

Ability to hear and recognize various alarms emitting from work area systems

Ability to hear and/or understand conversations

Ability to work in a darkroom for processing film, etc

Ability to be qualified physically for respirator use, initially and annually

Ability to work rotating shifts as required

Ability to work overtime as required

Ability to learn and use new processes, tools and equipment as required

Preferred

Experience in one or more of the following desired: proteomics, chromatography, mass spectrometry, tandem mass spectrometry, trapped ion mobility, orbitrap, isotopic labeling, DIA, DDA, post-translational modifications

Company

MUSC Health

MUSC Health provides health-care services through its patient- and family-centered care, education, research, and various partnerships. It is a sub-organization of Medical University of South Carolina.

Founded in 1824

Charleston, South Carolina, USA

10001+ employees