Poseida Therapeutics, Inc. · 4 months ago
Senior Director, Nanotechnology
Towne Centre
Full-time
Onsite
Senior Level, Lead/Staff, Director/Executive
$185K/yr - $344K/yr
15+ years expPoseida Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on advancing allogeneic cell therapies and genetic medicines. They are seeking a Senior Director of Nanotechnology to lead research efforts in nanoparticle formulation and LNP-mediated nucleic acid delivery, collaborating with various teams to optimize drug delivery systems and advance therapeutic applications.
BiopharmaBiotechnologyGeneticsTherapeutics
Responsibilities
Lead all research efforts for nanoparticle formulation, analytical characterization, and primary functional evaluation
Discover and optimize applications of novel lipids from diverse structural families for LNP-mediated delivery of nucleic acid payloads
Co-lead screening efforts, in vitro and in vivo, working closely with molecular and in vivo pharmacology groups, to identify novel LNP formulations for optimal tissue/cell delivery
Collaborate with diverse groups across the organization, including those representing cell therapy, vector engineering, pharmacology, translational biology, immuno-oncology, CMC, process development, and small molecule subject matter experts
Study fundamental mechanisms of action including LNP circulation, cellular uptake, endosomal escape, and specific behaviors unique to a particular payload class
Lead efforts to advance platform development for an in vivo therapeutic application of an LNP modality from concept through clinical validation
Analyze and interpret complex datasets, prepare clear reports, and present findings in internal program meetings, cross-functional reviews, and governance forums
Lead and contribute to external publications, conference abstracts, and patent filings relevant to LNP development for autoimmune, neurology, and oncology indications
Qualification
Required
Ph.D. in chemistry, engineering, bioengineering, nanotechnology, material science or a related field with 15+ years of relevant industry and academic experience
Experience working with T cells is required
Experience successfully advancing a candidate to IND-enabling studies is required
Proven expertise in nanoparticle science, especially LNP delivery systems and non-viral gene transfer/delivery
Strong data analysis skills and familiarity with design of experiments statistical analyses for process optimization, using software such as JMP statistical tools
Excellent communication, organizational, and leadership skills
Preferred
A strong background in DNA delivery is a plus
Familiarity with nucleic acids chemistry and molecular biology is highly desirable
Benefits
Excellent career development opportunities
Highly competitive compensation
Comprehensive benefits
Company
Poseida Therapeutics, Inc.
Poseida was acquired by Roche in early 2025 and is now part of the Roche Group.
201-500 employees
H1B Sponsorship
Poseida Therapeutics, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (6)
2024 (7)
2023 (4)
2022 (2)
2021 (3)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$460.45MKey Investors
Astellas PharmaFidelityNovartis
2024-11-26Acquired
2023-08-07Post Ipo Equity· $50M
2022-08-04Post Ipo Equity· $70M
Leadership Team
Mark Gergen
Chairman and Chief Executive Officer
Johanna Mylet
Chief Financial Officer
Recent News
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