Clinical Systems Architect jobs in United States
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Caris Life Sciences · 3 hours ago

Clinical Systems Architect

Caris Life Sciences is a company focused on transforming cancer care through precision medicine and cutting-edge technology. They are seeking a Clinical Systems Architect to serve as a technical bridge between application development and IT infrastructure teams, requiring expertise in CI/CD pipelines, cloud operations, and full-stack development. The role involves collaborating with various teams to deliver secure, scalable, and high-availability solutions.

Artificial Intelligence (AI)BiopharmaBiotechnologyHealth CareLife Science

Responsibilities

Lead the design and implementation of CI/CD pipelines with automated deployment strategies, SAST/DAST scanning, and infrastructure as code
Architect and maintain cloud-native solutions across AWS, GCP, or Azure, ensuring optimal performance and cost efficiency
Implement and manage security guardrails including authentication mechanisms, encryption protocols, and compliance frameworks (HIPAA, OIDC/OAuth 2.0)
Design and optimize networking solutions for high-availability, load balancing, and secure data transmission
Develop full-stack applications using Python and/or Node.js/Next.js with Vue.js or React
Integrate with monitoring and observability tools (Sentry, Datadog, NewRelic, Grafana) for comprehensive application performance management
Implement containerization strategies using Docker and Kubernetes for scalable deployments
Design and maintain RESTful APIs with security-first principles
Serve as the primary liaison between application development and IT teams (Networking, InfoSec, Cloud Operations)
Automate infrastructure provisioning and deployment processes using DevOps methodologies
Implement security scanning and monitoring throughout the development lifecycle
Collaborate with cloud operations teams to ensure seamless releases and incident response
Monitor incident tickets and determine resolution priority
Perform code reviews and offer constructive feedback
Provide technical/engineering support for existing applications, including code fixes
Analyze and solve complex technical problems, ensuring code quality, performance, and scalability
Collaborate with other departments (product management, quality assurance) for seamless product delivery
Assist management with timelines, resource estimates, and delivery details
Mentor and coach junior developers
Perform other related duties as assigned

Qualification

CI/CD pipelinesCloud architectureContainerization DockerContainerization KubernetesFull-stack developmentInformation securityNetworking principlesAPI designDatabase designAnalytical thinkingProblem-solving skillsCommunication skillsTeam collaboration

Required

Bachelor's degree in Computer Science, Software Engineering, or related field
5-7 years of DevOps & Infrastructure experience including expert-level proficiency in CI/CD methodologies and pipeline automation
5-7 years of Programming & Development experience with advanced Python programming and JavaScript/TypeScript expertise including Node.js, Vue.js, or React
Strong experience with containerization (Docker, Kubernetes preferred)
Proven track record in cloud architecture (AWS Lambda, SNS/SQS, S3, or equivalent GCP/Azure services)
Comprehensive understanding of networking principles and security protocols
Database design and optimization (MySQL, PostgreSQL, ORM technologies)
API design and security implementation (REST, authentication, encryption)
Deep knowledge of information security best practices and implementation
Experience with security scanning tools (SAST/DAST) and vulnerability management
Understanding of compliance frameworks (HIPAA, SOC 2, etc.)
Proficiency in implementing security protocols (OIDC/OAuth 2.0, encryption)
Version control systems (Git) and collaborative development workflows
Monitoring and alerting platforms (Grafana, Sentry, Datadog, NewRelic)
Infrastructure automation and configuration management
Performance optimization and scalability planning
Excellent problem-solving skills, analytical thinking, strong communication skills, and ability to work collaboratively in team-oriented environments

Preferred

Experience with AI-assisted development tools (Cursor AI)
Advanced networking and security certifications (CISSP, CCNA, AWS Security)
Experience with service mesh technologies and microservices architecture
Knowledge of data pipeline architecture and ETL processes
Experience with incident response and disaster recovery planning
Demonstrated capability to independently diagnose, analyze, and resolve complex issues related to application software
Skilled in ensuring HIPAA compliance, improving patient outcomes, and maintaining quality assurance standards while adhering to regulatory requirements

Company

Caris Life Sciences

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Caris Life Sciences develops molecular profiling and AI-driven technologies to support precision medicine in oncology.

Funding

Current Stage
Public Company
Total Funding
$1.86B
Key Investors
BraidwellOrbiMedSixth Street
2025-06-18IPO
2025-04-07Private Equity· $168M
2023-01-19Debt Financing· $400M

Leadership Team

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Luke Power
Chief Financial Officer
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Brian Stengle
SVP, Chief Marketing Officer
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Company data provided by crunchbase