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Arc Institute · 20 hours ago

Infrastructure Engineer

Palo Alto, CA

Full-time

Hybrid

Mid, Senior Level

$158K/yr - $196K/yr

Arc Institute is a new scientific institution focused on basic science and technology development to tackle complex human diseases. They are seeking an Infrastructure Engineer responsible for designing and optimizing their Hybrid Cloud Infrastructure Platform, collaborating with researchers and IT professionals to ensure system performance and support various bioinformatic projects.

BiotechnologyNon ProfitTraining

H1B Sponsor Likely

Responsibilities

Design and implement scalable data pipelines for single-cell genomics, experimental datasets, and bioinformatics workflows using tools like Nextflow, Prefect, or GCP Cloud Workflows

Build and maintain ExperimentDB from 0-1, establishing database architecture, data models, and APIs to support experimental data capture and retrieval across the institute

Develop data discovery infrastructure including catalog systems, metadata management, and data governance frameworks to enable scientists to find and access relevant datasets

Automate bioinformatics workflows and create agentic systems (e.g., automated single-cell analysis pipelines) that reduce manual intervention and accelerate research

Collaborate with scientists and engineers to understand data requirements, optimize query performance, and deliver tailored data infrastructure solutions

Establish best practices for data quality, versioning, and documentation to ensure reproducibility and reliability across research projects

Qualification

Workflow orchestration platformsDistributed systemsPythonSQLDatabase designBioinformatics toolsCuriosityProblem-solvingCommunication skills

Required

Bachelor's degree in Computer Science, Data Engineering, Bioinformatics, or a related field

Strong experience with workflow orchestration platforms (Nextflow, Prefect, Airflow, or similar) and building production data pipelines

Extensive experience with distributed systems, specifically data technologies: analytics warehouses, relational databases (PostgreSQL-based), object storage, and parallel/distributed file systems

Advanced skills in Python and SQL for data transformation, ETL processes, and API development

Experience with database design and optimization for scientific or analytical workloads at scale

Excellent problem-solving abilities and strong communication skills for translating scientific needs into technical solutions

Ability to work hybrid onsite (3 days per week) in Palo Alto, CA

Preferred

Familiarity with bioinformatics data formats and tools (FASTQ, BAM, Cell Ranger, single-cell analysis) is a strong plus

Benefits

Annual discretionary bonus

Company

Arc Institute

Arc Institute is a biomedical science and research technology company.

Founded in 2021

Palo Alto, California, USA

51-200 employees

https://arcinstitute.org

H1B Sponsorship

Arc Institute has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

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Trends of Total Sponsorships

2025 (14)

2024 (13)

2023 (3)