PRINCIPAL ENTERPRISE ARCHITECT - AI jobs in United States
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Sentara Health · 4 days ago

PRINCIPAL ENTERPRISE ARCHITECT - AI

Sentara Health is seeking a seasoned Enterprise Architect specializing in artificial intelligence (AI) to drive the design and integration of AI-powered solutions across their healthcare systems. The role involves defining AI architecture, establishing integration frameworks, and supporting AI initiatives to enhance clinical operations and patient engagement.

Hospital & Health Care
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H1B Sponsor Likelynote

Responsibilities

Drive the design, integration, and evolution of AI-powered solutions across healthcare back-office and enterprise systems
Define the end-to-end AI architecture and establish robust integration frameworks for multiple chatbots and AI services
Lay the foundations for scalable, future-ready capabilities that advance clinical operations, revenue cycle, and patient engagement
Map the relationships between information systems components (i.e., end users, business processes, applications, data, IT platform hardware/software, and networks)
Identify key interactions and dependencies across separate systems and platforms
Evaluate the total cost of ownership and return on investment of various architecture alternatives

Qualification

AI architectureAI/ML frameworksEnterprise architectureHealthcare experienceMLOps toolchainsAPI-first designMicroservices architectureData technologiesArchitecture frameworksAgile methodologiesDevSecOpsHealthcare interoperabilityData privacy regulationsEA tools

Required

8+ years in enterprise architecture or solution architecture roles, with a minimum of 4 years focused on AI/ML initiatives in healthcare or similarly regulated industries
Prior experience leading enterprise-wide AI transformation in a large health system or national healthcare provider
Proficient with AI/ML frameworks (TensorFlow, PyTorch), MLOps toolchains (Kubeflow, MLflow), and container orchestration (Kubernetes, Docker)
Deep understanding of API-first design, microservices architecture, messaging patterns (Kafka, RabbitMQ), and event streaming
Demonstrated track record integrating conversational AI/chatbot technologies across multiple back-office and front-office systems
Experience in technologies such as Cloud (Azure), Datawarehouse, Data mart, Data Lake, Data Fabric, Machine learning, mobile, and digital experience technologies
Experience with tools such as SQL Server, MongoDB, CosmosDB, Data Synapse, Data Bricks, Snowflake, Event Grid, Event Hub, Tableau, Power BI etc
Experience with Architecture frameworks such as TOGAF, DODAF, Zachman, FEAF etc. and specifically tailoring them to data-driven and AI-driven architecture domains
Skilled in agile and DevSecOps methodologies for rapid, secure delivery of AI solutions
Familiarity with healthcare interoperability standards (FHIR, HL7) and data privacy regulations (HIPAA, GDPR)
Experience modeling architecture viewpoints in EA tools

Preferred

Experience supporting enterprise-level AI/ML initiatives
Knowledge of industry standards and frameworks (e.g., TOGAF, Zachman)
Background in healthcare or large-scale enterprise environments

Benefits

Medical, Dental, Vision plans
Adoption, Fertility and Surrogacy Reimbursement up to $10,000
Paid Time Off and Sick Leave
Paid Parental & Family Caregiver Leave
Emergency Backup Care
Long-Term, Short-Term Disability, and Critical Illness plans
Life Insurance
401k/403B with Employer Match
Tuition Assistance – $5,250/year and discounted educational opportunities through Guild Education
Student Debt Pay Down – $10,000
Reimbursement for certifications and free access to complete CEUs and professional development
Pet Insurance
Legal Resources Plan
Colleagues may have the opportunity to earn an annual discretionary bonus if established system and employee eligibility criteria is met

Company

Sentara Health

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Sentara Health, an integrated, not-for-profit health care delivery system, celebrates more than 135 years in pursuit of its mission - "we improve health every day." Sentara is one of the largest health systems in the U.S.

H1B Sponsorship

Sentara Health has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (30)
2024 (7)
2023 (1)

Funding

Current Stage
Late Stage

Leadership Team

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Dennis Matheis
President & CEO
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Howard Kern
CEO Emeritus Sentara Health
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Company data provided by crunchbase