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Calico Life Sciences · 23 hours ago

Principal Investigator, Cardiovascular Research

South San Francisco, CA

Full-time

Onsite

Senior Level, Lead/Staff

$220K/yr - $241K/yr

5+ years exp

Calico Life Sciences is an innovative research and development company focused on understanding human aging and developing interventions to promote healthier lives. They are seeking a highly motivated Principal Investigator for Cardiovascular Research to lead laboratory investigations and drug development efforts targeting age-related cardiovascular diseases.

Responsibilities

Lead and mentor a group of talented scientists as a laboratory team focused on cardiovascular diseases of aging aimed at drug target identification and validation

Develop and execute innovative research strategies to identify and validate novel drug targets

Oversee the design and implementation of in vitro and in vivo studies for proof of concept for new therapeutics

Collaborate with cross-functional teams, including medicinal chemistry, biology, and translational research, to advance drug discovery programs

Stay abreast of the latest scientific advancements in cardiovascular disease and aging biology and related advances in drug discovery

Represent the company at scientific conferences and meetings

Qualification

Cardiovascular biologyAging researchDrug discoveryVitro modelsVivo modelsCreative thinkingCritical thinkingCommunication skillsInterpersonal skills

Required

MD/PhD preferred, MD or PhD in molecular biology, biochemistry, disease pathogenesis, or a related field, with emphasis on the mechanisms of cardiovascular or other aging-related diseases

Rising or proven leader with 5-10 years of experience in cardiovascular research, with a track record of success in cutting edge discoveries and impactful publications and/or patents and national or international recognition

Extensive knowledge of cardiovascular biology and aging-related disease mechanisms

Experience with in vitro and in vivo cardiovascular disease model systems

Creative and critical thinking, excellent communication, presentation, and interpersonal skills

Ability to work independently and as part of a team in a fast-paced environment

Creative and critical thinking skills

Must be willing to work onsite five days a week

Preferred

Understanding of drug discovery processes, including target identification, assay development, high-throughput screening, and lead optimization

Familiarity with various “-omics” technologies (genomics, proteomics, metabolomics)

Experience with in vivo models of aging and age-related diseases

Benefits

Two annual cash bonuses

Company

Calico Life Sciences

Glassdoor4.1

Calico is an Alphabet-founded research and development company whose mission is to harness advanced technologies.

Founded in 2013

South San Francisco, California, USA

201-500 employees

http://www.calicolabs.com/

H1B Sponsorship

Calico Life Sciences has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

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2020 (14)