Cellares · 1 hour ago
Staff Systems Engineer
South San Francisco, CA
Full-time
Onsite
Lead/Staff
$90K/yr - $210K/yr
10+ years expCellares is an Integrated Development and Manufacturing Organization focused on cell therapy systems. The Staff Systems Engineer will apply systems-thinking to design and develop innovative instruments, collaborating with cross-functional teams to oversee high-value internal projects from requirements capture to verification and validation activities.
BiotechnologyLife ScienceManufacturingMedicalTherapeutics
Responsibilities
Responsible for developing, maintaining, and refining system requirements and architecture
Create and maintain documents, models & diagrams describing functional and physical decompositions, interface definitions, and flow diagrams
Responsible for developing, maintaining, and executing system and subsystem design verification protocols
Lead small project teams developing Cellares technology or testing strategies
Mentor junior members of the Systems Engineering team on best engineering practices
Support architecture definition by working with subsystem design teams to align overlapping design requirements, constraints, and drive teams in developing concepts, evaluating risks, and efficiently converging on a design path
Translate architectural concepts into prototypes, integrate them, analyze results, and iterate on the design
Work closely with product management to interpret customer, business, and compliance needs to define technical requirements
Develop system models that guide design decisions. These can include system tolerance budgets, performance models, COGS models, etc
Provide support to sub-system engineers in the development of models that guide lower-level design decisions
Develop test systems for internal use to support both R&D experiments and pilot build testing needs
Conduct design reviews and present fresh ideas, new technologies, and creative solutions to design problems
Using a structured approach for problem solving, lead teams through complex root-cause analysis in which there are many possible root causes that involve various areas of physics and engineering
Qualification
Required
Bachelor's, Master's, or PhD in Physics or Engineering with 10+ years of extensive and hands-on experience in the development of analytical instrumentation, biotech automation, or similar is required
Hands-on experience designing and integrating in the lab highly complex instrumentation prototypes that combine fluidic handling, electronic sensors, or robotics
Working knowledge of requirements and risk management tools like JamaConnect, IBM Doors, TeamCenter, Orcanos, or Helix
Experience with MATLAB, Python, or high-level scripting software languages for modeling, simulation, and data processing
Working knowledge of Statistical Design of Experiments, Data Analysis and Visualization, with SW tools such as JMP, Minitab, and Tableau
Excellent verbal, written, presentation, and interpersonal skills
Strong analytical and problem-solving skills
Demonstrated track record of rapidly climbing steep learning curves
Prior experience working in ISO regulated environments (ISO 13485, ISO 14791)
Creative, self-motivated, and flexible to work in a small company environment and assume a wide variety of tasks
Desire to be part of a rapidly evolving organization, with a compelling technology, and taking products and processes to the next level
Self-awareness, integrity, authenticity, and a growth mindset
Preferred
Specific expertise in bioprocessing technologies involved in cell therapy manufacturing
Benefits
Highly subsidized Medical, Dental, and Vision Plans
401(k) Matching
Free EV Charging
Onsite lunches
Stock options
Company
Cellares
Cellares is a life sciences technology company that develops the Cell Shuttle to automate cell therapy manufacturing.
51-200 employees
H1B Sponsorship
Cellares has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (2)
2023 (2)
2022 (1)
2020 (1)
Funding
Current Stage
Growth StageTotal Funding
$355MKey Investors
Koch Disruptive TechnologiesEclipse Ventures
2023-08-23Series C· $255M
2021-05-05Series B· $82M
2020-10-29Series A· $18M
Leadership Team
Fabian Gerlinghaus
Co-Founder and CEO
Omar Kurdi
Co-Founder and President
Recent News
2025-12-01
Company data provided by crunchbase