Kymera Therapeutics · 2 days ago
Senior Director or Executive Director, Toxicology
Greater Boston
Full-time
Onsite
Director/Executive
$235K/yr - $335K/yr
12+ years expKymera Therapeutics is a clinical-stage biotechnology company pioneering the field of targeted protein degradation. They are seeking an experienced nonclinical toxicologist to oversee the strategy, design, analysis, interpretation, and reporting of Toxicology and Safety Pharmacology data for discovery and development teams.
BiotechnologyHealth CareMedicalTherapeutics
Responsibilities
Provide expert nonclinical safety support, guidance, and strategy for Kymera’s degrader projects, ranging from discovery programs to advanced clinical programs
Act as the key nonclinical safety representative on cross-functional development teams contribute nonclinical safety-related scientific and regulatory expertise to drive integrated program decision-making
Develop nonclinical safety strategies and plans for programs in all stages of drug development
Oversee toxicology and safety pharmacology studies at multiple Contract Research Organizations
Design and execute GLP, non-GLP, investigative, and in vitro studies
With internal Study Monitor support, oversee toxicology studies for appropriate conduct, accuracy, and timely execution; review draft protocols and reports and ensure quality submission-ready documents for regulatory authorities
Internal and external communication
Prepare verbal and written summaries for internal discussions. Work with the Preclinical Development team to develop optimal strategies to address specific safety issues and partner with project teams
Lead authorship of toxicology and/or safety pharmacology sections of various regulatory documents (e.g., pre-IND briefing documents, IND, IBs etc.)
Represent company at meetings with regulatory agencies
Present summary data to project teams and Kymera senior leadership
Provide leadership and mentorship to junior toxicology or preclinical staff as the team grows; foster a culture of scientific excellence
Qualification
Required
PhD in Toxicology or Pharmacology, DVM, or related field
12+ years of experience in the biopharma industry in a Toxicology or Pathology role including ≥ 5 years supporting small molecule project teams leading preclinical development strategy for IND-through-Phase II programs
Experience with EMA and FDA CTA/IND submissions and regulatory interactions
Experience partnering with internal stakeholders and colleagues to ensure comprehensive preclinical safety approaches are developed as part of the program strategy
Strong verbal and written communication skills with the ability to influence and present to executive leadership and external stakeholders, including regulatory agencies
Experience working with outsourced studies
Ability to perform in fast-paced and dynamic environment
Preferred
DABT or ERT certification preferred, but not required
Benefits
Eligibility for annual bonus
Equity participation
Comprehensive benefits
Company
Kymera Therapeutics
Kymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation.
51-200 employees
H1B Sponsorship
Kymera Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (2)
2023 (4)
2022 (3)
2021 (3)
Funding
Current Stage
Public CompanyTotal Funding
$1.96BKey Investors
Biotechnology Value FundAtlas Venture
2025-12-10Post Ipo Equity· $602M
2025-06-26Post Ipo Equity· $250.8M
2024-08-19Post Ipo Equity· $225M
Leadership Team
Nello Mainolfi
Founder, President and Chief Executive Officer
Jeremy Chadwick
Chief Operating Officer
Recent News
2025-12-11
Company data provided by crunchbase