Scientist / Sr. Scientist jobs in United States
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Until · 4 months ago

Scientist / Sr. Scientist

Until is a moonshot company focused on developing a 'pause button' for biology, with an emphasis on organ-scale reversible cryopreservation. The Scientist/Senior Scientist will advance cryopreservation formulations through high-throughput experiments and may lead projects and mentor junior team members.

BiotechnologyLife Science

Responsibilities

Develop innovative approaches to characterize toxicity and permeability of new compounds and their interactions with cells and organs
Build clinically translatable healthy in vitro models using primary cells/tissues (Kidney, Liver, Heart, etc.)
Design and implement high-throughput screening (HTS) experiments at cellular, 3D in vitro model, and tissue levels
Analyze HTS data to identify promising materials and biological interactions that support project objectives
Apply genomics techniques such as GWAS, RNAseq, and FISH to inform and refine molecular discovery and in vitro models
Collaborate closely with cross-functional teams to translate experimental findings into new cryoprotectant solutions for human-sized organ preservation

Qualification

CryopreservationHigh-throughput screeningPrimary cell cultureGenomics techniquesLiquid handling roboticsChemical characterizationPharmacokineticsPharmacodynamicsCollaborationProblem-solving

Required

4+ years of industry experience or PhD/Postdoc training in Bioengineering, Synthetic Biology, Chemical Engineering, Biochemistry, Neuroscience, Immunology, or a related field
A track record of scientific excellence and autonomy, with the ability to independently develop and carry out complex experiments
A collaborative mindset and value diverse perspectives
Experience with primary cell culture and tissues (Kidney, Liver, Heart, etc.)
Balance of technical expertise and creative problem-solving to uncover novel materials, explore biomaterial–biology interactions, and develop innovative biological mechanisms to enhance performance
Develop innovative approaches to characterize toxicity and permeability of new compounds and their interactions with cells and organs
Build clinically translatable healthy in vitro models using primary cells/tissues (Kidney, Liver, Heart, etc.)
Design and implement high-throughput screening (HTS) experiments at cellular, 3D in vitro model, and tissue levels
Analyze HTS data to identify promising materials and biological interactions that support project objectives
Apply genomics techniques such as GWAS, RNAseq, and FISH to inform and refine molecular discovery and in vitro models
Collaborate closely with cross-functional teams to translate experimental findings into new cryoprotectant solutions for human-sized organ preservation

Preferred

Expertise in developing and maintaining advanced in vitro models to support discovery and translational research
Proficiency with genomics platforms and analytical methods (e.g., GWAS, RNA sequencing, FISH)
Skilled in programming and operating liquid handling robotics to enable high-throughput workflows
Strong command of instrumentation techniques for chemical characterization, including DSC, HPLC, GC/LCMS, and FPLC
Demonstrated ability to evaluate drug pharmacokinetics and pharmacodynamics to inform preclinical development

Company

Until

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We are building reversible cryopreservation technology to solve the organ procurement and matching problem.

Funding

Current Stage
Early Stage
Total Funding
$106M
Key Investors
Founders Fund
2025-09-22Series A· $58M
2024-06-06Series A· $48M

Leadership Team

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Hunter Davis
Co-founder, CSO
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Company data provided by crunchbase