Neurocrine Biosciences · 18 hours ago
Sr. Principal Scientist, Analytical Development (Small Molecule San Diego Based)
San Diego, CA
Full-time
Onsite
Senior Level, Lead/Staff
$157K/yr - $214K/yr
7+ years expNeurocrine Biosciences is a leading neuroscience-focused biopharmaceutical company dedicated to discovering and developing life-changing treatments for patients. The Sr. Principal Scientist will lead a sub-team in analytical development and guide analytical activities for drug substance and product development, ensuring compliance with regulatory requirements and advancing innovation in analytical techniques.
BiotechnologyHealth CarePharmaceutical
Responsibilities
Leads and manages multiple projects. Represents Analytical Development on cross-functional teams. Maintains accountability for analytical deliverables and progress on CMC plans for all development projects
Manages designs, plans and executes activities towards the goals of one or more analytical development projects to support pre-clinical through commercial activities
Directs laboratory work and/or lab personnel and ensures safe laboratory practices
Performs analytical development and optimizes methods in support of preclinical through commercialization
Creates and implements novel ideas and techniques to support analytical activities with Chemical and Product Development
Develop and support off-site analytical transfers, manufacturing support and interaction with contractors
Supplies input into CMC regulatory documentation and supporting work
Facilitates effective supervision of laboratory personnel and guidance for their professional development
Leverages literature, ICH/ Regulatory guidance, and practical experience to perform their work and influence CMC strategies
Contributes to development of policies and department strategies
Builds and enhances internal and external professional relationships
Supports career development and technical growth of direct reports
Presents finding at varying levels across the company
Other duties as assigned
Qualification
Required
BS/BA in Analytical Chemistry or related discipline and 15+ years of experience in the analytical/pharmaceutical development field. Experience in method transfer in Analytical Chemistry OR
MS/MA in Analytical Chemistry or related discipline and 13+ years of experience OR
PhD in Analytical Chemistry or related discipline and 7+ years of relevant experience; may include postdoc experience
Expert knowledge and understanding of analytical chemistry and a thorough understanding of process chemistry as well as formulation development
Excellent interpersonal skills with strong oral and written communication abilities
Excellent laboratory and productivity skills
Method development, validation, and transfer experience in Analytical Development
Comprehensive understanding of cGMP requirements in API and drug product
Expert knowledge of cross-functional understanding related to drug development
Applies understanding of the team's place in the larger organization, and discusses changes, progress, and issues as they relate to other areas
Maintains substantial knowledge of principles and theories and acts as a technical lead on various projects
Leads the development of intellectual property
May utilize working knowledge of other related disciplines to provide solutions to a wide range of difficult problems
Ability to work as part of and lead multiple teams
Good leadership, mentoring skills and abilities typically leads lower levels and/or indirect teams
Excellent communications, problem-solving, analytical thinking skills
Sees broader picture and longer-term impact on division/company
Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency
Excellent project management, strong project leadership skills
Benefits
Annual bonus with a target of 30% of the earned base salary
Eligibility to participate in our equity based long term incentive program
Retirement savings plan (with company match)
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans
Company
Neurocrine Biosciences
Neurocrine Biosciences engages in the discovery and development of drugs for the treatment of neurological and endocrine-related diseases.
1001-5000 employees
H1B Sponsorship
Neurocrine Biosciences has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (16)
2024 (9)
2023 (8)
2022 (2)
2021 (5)
2020 (6)
Funding
Current Stage
Public CompanyTotal Funding
$260MKey Investors
Venrock
2015-02-19Post Ipo Equity· $250M
2009-12-17Post Ipo Equity· $10M
1996-05-31IPO
Leadership Team
Matt Abernethy
Chief Financial Officer
D
Dimitri Grigoriadis
VP, Research
Recent News
2026-01-06
Company data provided by crunchbase