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Lawrence Livermore National Laboratory · 3 months ago

Senior Protein Design Scientist

Livermore, CA, USA

Full-time

Onsite

Senior Level

$202K/yr - $308K/yr

Lawrence Livermore National Laboratory is seeking a Senior Protein Design Scientist to advance R&D initiatives within the Center for Predictive Bioresilience. The role involves driving protein engineering programs, integrating computational and experimental methods, and collaborating with multidisciplinary teams to develop medical countermeasures and biotechnological innovations.

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Growth Opportunities

No H1B

Security Clearance Required

U.S. Citizen Only

Responsibilities

Provide technical leadership for protein design and engineering programs, setting strategy and direction for multidisciplinary teams

Develop, implement, and provide highly advanced biotechnical analysis and solutions to resolve highly complex biotechnical and programmatic issues

Architect and execute R&D strategies for protein engineering and biocatalysis platforms, integrating bioinformatics, analytics, and chemistry

Develop and implement innovative AI/ML pipelines for enzyme engineering and high-throughput experimental validation

Provide highly advanced guidance and mentorship to scientists across biochemistry, microbiology, bioinformatics, and analytical chemistry, fostering and supporting their technical growth and collaboration

Oversee operational management, optimizing project workflows, reducing cycle times, and improving program efficiency

Coordinate and interface directly with senior management and external sponsors to communicate technical milestones, solicit input from, and provide advice to leaders in the program

Utilize technical expertise and analytical skills to communicate results through formal and complex technical reports, presentations, and peer-reviewed scientific journals as appropriate

Lead the launch and execution of research programs and strategic partnerships with Contract Manufacturing Organizations (CMOs), pharmaceutical, industrial, and government partners, spanning diverse applications to expand capabilities and support commercialization

Drive platform innovation, deploying new technologies in analytical chemistry, cell line development, and direct-to-biology screening

Secure external funding by co-authoring grant proposals and leading strategic collaborations to advance core technologies

Perform other duties as assigned

Serve as a subject matter expert, providing scientific and technical direction for highly complex and sensitive protein design projects

Champion the development and deployment of revolutionary methods and technologies, influencing the future direction of the organization and the field

Advise senior management and external stakeholders on strategic technical decisions, representing the organization as the senior technical expert in high-impact collaborations and committees

Qualification

Enzyme engineeringAI/ML integrationHigh-throughput screeningBiocatalysisBioinformaticsProject managementTechnical communicationStrategic planningTeam leadershipCollaboration skills

Required

PhD in Chemistry, Biochemistry, or a related scientific or technical field or the equivalent combination of education and related experience

Expert-level knowledge and application of enzyme engineering, directed evolution, high-throughput screening, and biocatalysis. Significant experience with a broad range of bioengineering applications, such as biotherapeutics, biosensors, and vaccines

Significant experience in developing and implementing R&D strategies for platform technologies

Significant experience and background and demonstrated ability to successfully lead multidisciplinary scientific teams and manage complex research programs

Demonstrated ability to integrate computational and experimental approaches, including AI/ML and bioinformatics

Proven success in launching and managing collaborative research programs with external partners

Expert-level strategic planning, organizational, and project management skills, with the ability to manage complex initiatives across multiple stakeholders

Expert verbal and written communication skills and significant experience in preparing highly complex analyses and successfully delivering highly advanced technical presentations, as well as expert facilitation and collaboration skills to effectively influence and advise senior management and external sponsors