Elanco · 3 months ago
Manufacturing Principal Engineer
Indianapolis, IN
Full-time
Hybrid
Lead/Staff
8+ years expElanco is a global leader in animal health dedicated to innovation and delivering products to improve the lives of animals. The Manufacturing Principal Engineer will be responsible for shaping the digital transformation of manufacturing, designing the digital backbone of factories, and ensuring systems drive business value while mentoring a team of engineers.
ManufacturingPetSupply Chain Management
Responsibilities
Design and own the architectural roadmap for Elanco's enterprise-wide MES/LES platforms
Lead initiatives to re-engineer critical manufacturing and lab processes through the strategic application of digital technology
Establish and govern engineering standards and design patterns for MES/LES development, aligned with industry frameworks like GAMP 5
Define the integration strategy for MES/LES with the broader enterprise systems landscape
Develop and oversee the global validation strategy for all manufacturing systems
Serve as a trusted advisor to site and global leadership
Proactively identify and evaluate emerging Pharma 4.0 trends and lead proof-of-concept projects
Qualification
Required
A Bachelor's or Master's degree in Engineering (e.g., Industrial, Chemical, Manufacturing, Computer Science) or a related technical field
8+ years experience. A significant and proven track record leading the design, implementation, and lifecycle management of complex MES/LES solutions within a large-scale pharmaceutical, biologics, or animal health manufacturing environment
Expert-level knowledge of industry-leading MES platforms (e.g., Werum PAS-X, Emerson Syncade, POMSnet) and their application in life science manufacturing, including electronic batch records (EBR) and review-by-exception
Demonstrated leadership in a highly regulated GxP environment, with deep expertise in pharmaceutical production processes (e.g., sterile/aseptic processing, vaccine manufacturing, quality control testing) and their associated data integrity requirements
Proven ability to develop multi-year technology roadmaps that align with business strategy and deliver measurable improvements in cost, quality, and speed
Experience mentoring and developing other engineers, leading complex technical projects, and acting as the definitive subject matter expert for a team
Preferred
Knowledge of relevant DevSecOps concepts and tooling, including Continuous Integration/Continuous Delivery (CI/CD), Git SCM, Containerisation (Docker, Kubernetes), Infrastructure-as-Code (HashiCorp Terraform)
Practical experience with Public Cloud, specifically Microsoft Azure and Google Cloud Platform (GCP) and their Automation services (e.g., Azure Logic Apps)
Mastery of computer system validation (CSV) principles based on GAMP 5 and ASTM E2500. Direct experience successfully facing regulatory audits from agencies like the FDA, EMA, and USDA
Ability to articulate a compelling vision for manufacturing technology to diverse audiences, from shop-floor engineers to senior executive leadership
Benefits
Multiple relocation packages
Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)
8-week parental leave
9 Employee Resource Groups
Annual bonus offering
Flexible work arrangements
Up to 6% 401K matching
Company
Elanco
Elanco is an animal health company that manufactures and markets a diverse range of products to promote animal health and well-being.
5001-10000 employees
H1B Sponsorship
Elanco has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (9)
Funding
Current Stage
Public CompanyTotal Funding
$252.86MKey Investors
AncoraBill & Melinda Gates Foundation
2023-12-30Post Ipo Equity· $250M
2018-09-19IPO
2017-05-24Grant· $2.86M
Leadership Team
Dave Kinard
Executive Vice President Human Resources, Corporate Affairs & Administration
Jennifer Black
Senior Director, Global Indirect Procurement
Recent News
2026-01-03
2025-12-18
Company data provided by crunchbase