Amgen · 4 months ago
MES Application Owner - Systems Engineer
US - North Carolina - Holly Springs
Full-time
Hybrid
Mid, Senior Level
$143K/yr - $163K/yr
4+ years expAmgen is a leading biotechnology company dedicated to serving patients living with serious illnesses. The MES Application Owner - Systems Engineer will manage and support Business and Automation platforms, focusing on system administration, configuration, and maintenance while collaborating with business partners to optimize manufacturing processes.
BiotechnologyHealth CareManufacturingPharmaceutical
Responsibilities
Own the ongoing creation and roadmap for the Business and Automation platform applications, including system administration, configuration, and maintenance (i.e., MES Korber PAS|X, Emerson Delta V, Rockwell, Siemens, OSISoft PI, VeevaVault, iWAREHOUSE, VirTECS, Autodesk BIM 360) preferably biotechnology, pharmaceutical, or related industry
Collaborate with business partners and other technology professionals to develop and deploy the latest, advanced technologies in support of product manufacturing optimization
Collaborate with the rest of the manufacturing network to incorporate lessons learned and share ongoing best practices and with the business partners to understand how automation can improve workflow and productivity
Manage and/or support the execution of a varied portfolio of DTI projects with appropriate portfolio planning, resource and risk management and financial management for the portfolio
Work closely with the delivery and platform teams to ensure that the applications are aligned with standard city planning approved architectural and development guidelines
Lead selected efforts to design, build, and develop rapid Proof-of-Concept (POC) automated solutions and services. Quickly and iteratively prove or disprove the concepts being considered
Synthesize requirements from end-users, application architects, and cybersecurity experts to develop the best automation solutions
Work closely with the business and DTI Manufacturing System Engineers to identify opportunities to stop inefficient practices, simplify business processes, and codify into automated solutions and platforms
Ensure all work is completed within GMP regulations
Qualification
Required
Doctorate degree, OR
Master's degree and 2 years of Information Systems, Engineering and/or Information technology experience, OR
Bachelor's degree and 4 years of Information Systems, Engineering and/or Information technology experience, OR
Associate's degree and 8 years of Information Systems, Engineering and/or Information technology experience, OR
High school diploma/GED and 10 years of Information Systems, Engineering and/or Information technology experience
Preferred
Industry experience with utilities/manufacturing software development or management that support manufacturing, (i.e., MES Korber PAS|X, Emerson Delta V, Rockwell, OSISoft PI, VirTECS) preferably biotechnology, pharmaceutical, or related industry
Educational background in Computer Science, Engineering, Information Systems, or others related fields
5+ years' experience designing, developing, deploying, and operating automated solutions across SaaS, Cloud, On-prem and custom software developed platforms
Knowledge of several industry 4.0 technologies including, but not limited to Process Modeling and Simulation, Data Driven Process Control, Internet of Things, Automated Warehouse solutions, and Automated Guided Vehicles. Methods and technologies to support
Manufacturing Data integrations (e.g., SQL, Web Services/messaging, data mapping)
Hands-on experience with computerized systems including troubleshooting, reliability, and performance improvements. Experience with Process Design/Configuration and Commissioning
Proficient technical writing and presentation skills to communicate sophisticated information effectively with technical and senior management staff
Expertise with translating business requirements/user stories to technical requirements and recommend solutions for automation
Experience with Data analysis and reporting experience by using analytics, visualization, and database technologies
Experience or solid understanding of current Good Manufacturing Practices (cGMP), 21CFR Part 11 regulations, change control and validation
Willing and able to learn new technologies at a rapid pace Experience in supporting key manufacturing systems with 24×7 operations individually and with vendors
Experience with Agile Product Development delivery and SAFe practices
Benefits
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible
Company
Amgen
Amgen is a biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases.
10001+ employees
H1B Sponsorship
Amgen has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (429)
2024 (485)
2023 (485)
2022 (540)
2021 (460)
2020 (444)
Funding
Current Stage
Public CompanyTotal Funding
$28.5B2022-12-12Post Ipo Debt· $28.5B
1983-06-17IPO
Leadership Team
Robert Bradway
Chairman and Chief Executive Officer
Jay Bradner
Executive Vice President of R&D, and Chief Scientific Officer
Recent News
2026-01-11
FierceBiotech
2026-01-11
The Motley Fool
2026-01-09
Company data provided by crunchbase