Revolution Medicines · 3 months ago
Senior Clinical Scientist
Redwood City, California, United States
Full-time
Onsite
Senior Level
$144K/yr - $180K/yr
6+ years expRevolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. They are seeking a Senior Clinical Scientist to join their Clinical Development team, primarily focusing on GI oncology, where the individual will oversee the design, execution, analysis, and reporting of clinical trials while ensuring data accuracy and regulatory compliance.
Health CareLife ScienceMedical
Responsibilities
Drive clinical data review and cleaning activities, ensuring medical and scientific accuracy in patient-level data prior to database lock
Experience in preparation and/or review patient’s narratives (mini narratives and full narratives) for NDA/BLA submissions
Collaborate with Clinical Data Management to define data cleaning strategies, edit checks, and reconciliation processes across efficacy, safety, and biomarker datasets
Lead or co-lead clinical data review meetings, escalating scientific issues, resolving discrepancies, and ensuring traceability for regulatory filings
Strong working knowledge of data cleaning, database lock processes, and clinical data review
Proven ability to lead cross-functional clinical teams and contribute to strategic development plans
Contribute to clinical development strategy and execution of the Clinical Development Plan (CDP) with a focus on early-phase development
Contribute to the clinical data content of NDA, BLA, and MAA dossiers, including clinical study reports (CSRs), integrated summaries of safety/efficacy (ISS/ISE), and module 2.7 (2.7.3, 2.7.4, 2.7.5) of submission documents
Support regulatory agency interactions by preparing briefing documents, contributing to responses, and ensuring scientific consistency across submission components
Partner with cross-functional teams with oversight from senior team members to conduct clinical studies, including study start up, execution and close out activities, data review/analysis, and preparation of study reports
Contribute to the development of program-level documents, including but not limited to clinical protocols, investigator’s brochure, clinical study reports, abstracts and manuscripts, presentations, and various other internal and external documents and communications as needed
Conduct ongoing data reviews; prepare and present summaries to internal and external stakeholders
Ensure trial implementation according to the protocol and analyze information to assess issues relating to protocol conduct and/or individual subject safety
Interact with internal and external stakeholders (investigators, study sites, vendors, committees, etc.) in support of clinical trial objectives; responds to or triages questions for appropriate escalation
Conduct literature reviews as needed
Travel: Up to 20%
Qualification
Required
BS/BA or master's degree in a scientific discipline, or other relevant advanced degree in a health science field. Preferred M.D. (or equivalent medical degree MBChB, MBBS)
Minimum 6 years of experience in the pharmaceutical or biotechnology industry as a clinical scientist or related role
Minimum of 4 years' experience supporting or leading data review and cleaning activities for NDA/BLA/MAA submissions in oncology or related therapeutic areas
Familiarity with statistical outputs and data visualization tools (e.g., Spotfire, R, SAS)
Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high-energy environment
Detail-oriented with ability prioritize tasks and function independently as appropriate
Strong organizational skills and an ability to interpret, discuss, and report trial/program level data effectively and identify trends
Proficient with software tools (Microsoft Office), Electronic Data Capture, and other custom web-based software
Excellent written and verbal communication skills
Preferred
Strong experience with clinical data review and data quality assurance
Knowledge and experience with clinical trial management and oversight, data cleaning, review and verification processes
Understanding and experience in clinical trial protocol and regulatory document authoring
Benefits
Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities
Company
Revolution Medicines
Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.
501-1000 employees
H1B Sponsorship
Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$2.25BKey Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M
Leadership Team
Luan Wilfong
Chief Human Resources Officer
Steve Kelsey
President
Recent News
Pharmaceutical Technology
2026-01-13
Company data provided by crunchbase