Scholar Rock · 5 hours ago
Head of Biomarker Development
Cambridge, MA
Full-time
Onsite
Director/Executive
$240K/yr - $330K/yr
10+ years expScholar Rock is a biopharmaceutical company focused on developing life-changing therapies for serious diseases. They are seeking a strategic scientific leader to shape and execute the biomarker strategy across their pipeline, enabling translation from discovery through clinical development in neuromuscular and rare diseases.
BiopharmaBiotechnologyMedicalTherapeutics
Responsibilities
Define and drive the biomarker development strategy across preclinical and clinical programs, ensuring alignment with overall portfolio goals
Serve as a translational science thought leader, integrating biomarker approaches into program strategy, clinical development plans, and indication expansion activities
Represent Biomarker Development in cross-functional governance and portfolio planning forums
Lead the design, development, and qualification of fit-for-purpose biomarker assays (fluid, tissue, imaging, molecular, and cellular)
Oversee biomarker implementation in preclinical models and clinical studies, ensuring robust data generation and interpretation
Manage CROs and external collaborators/vendors to deliver high-quality biomarker data
Collaborate with discovery teams to translate preclinical biomarker hypotheses into clinically actionable endpoints
Provide expertise on novel technologies (e.g., immunoassays, LC-MS, SIMOA, RNA-seq, digital pathology, imaging biomarkers, multiparameter flow cytometry)
Contribute to the design of biomarker plans within clinical study protocols, informed consent forms, and statistical analysis plans
Author and review biomarker sections of INDs, CTAs, IBs, CSRs, and other regulatory filings
Present biomarker data and strategy to internal stakeholders, governance committees, external partners, and regulatory agencies
Qualification
Required
PhD in biology, immunology, neuroscience, pharmacology, or related discipline
10+ years of experience in biotech/pharma R&D with a strong track record in biomarker discovery and development, including translational application in clinical trials
Demonstrated leadership in developing and implementing biomarker strategies for rare diseases; experience in neuromuscular disorders strongly preferred
Proven expertise with a range of biomarker platforms (immunoassays, LC-MS, transcriptomics, imaging, flow cytometry, digital pathology, and molecular assays)
Familiarity with bioanalytical and regulatory requirements for biomarker integration in IND-enabling studies and clinical development
Experience managing CROs, external consultants, and collaborative teams
Strong leadership, interpersonal, and communication skills, with the ability to influence across levels and functions
Passion for rare disease research and a commitment to improving patients' lives
Company
Scholar Rock
Scholar Rock is a biopharmaceutical company that develops and discovers new medicines and treatments for the serious diseases.
51-200 employees
H1B Sponsorship
Scholar Rock has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (1)
2021 (4)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$743MKey Investors
InvusFidelityARCH Venture Partners
2024-10-08Post Ipo Equity· $300M
2023-10-11Post Ipo Equity· $85M
2022-06-17Post Ipo Equity· $205M
Leadership Team
Jay Backstrom
Chief Executive Officer
Recent News
Morningstar.com
2025-12-13
2025-11-25
Company data provided by crunchbase