Revolution Medicines · 3 months ago
Vice President, Disease Area Franchise Head, Clinical Development
Redwood City, California, United States
Full-time
Onsite
Director/Executive
$284K/yr - $355K/yr
15+ years expRevolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. As Franchise Head, you will lead clinical science teams to develop global clinical development plans and ensure effective execution for multiple molecules within the assigned disease area.
Health CareLife ScienceMedical
Responsibilities
Lead and own the global clinical development strategy and roadmap for the disease area (lung / colon / pancreas cancer), spanning preclinical through late-phase development, regulatory interactions, and support for eventual commercialization
Oversee execution of multiple molecule programs within the disease area: ensure high quality protocol design, site selection, patient recruitment, data integrity, regulatory compliance, and risk/benefit evaluation
Serve as clinical & scientific thought leader in the disease area: monitor external science, competitive intelligence, emerging modalities, biomarkers; integrate translational science into clinical programs
Act as a primary interface with regulatory authorities, KOLs, external experts/ advisory boards (domestic & international), for clinical strategy, plan negotiation, and feedback
Partner closely with cross-functional organizations including Research, Regulatory Affairs, Translational Medicine, Medical Affairs, Commercial, Operations, and Finance to ensure alignment of scientific, regulatory, and commercial objectives
Mentor, develop, recruit, and retain talent in your teams; provide leadership to direct reports and non-direct report team members. Ensure training, career development, and performance management
Manages direct reports and is accountable for hiring, training, developing, and retaining talent on his/her staff. Ensures consistent compliance with all governing employment laws, regulations, and RevMed HR policies and procedures. Demonstrates strong people leadership through delegating effectively, empowering teams, and ensuring accountability for high-quality outcomes. Prior people-management experience is required, with a proven ability to motivate, coach, and lead both direct and indirect team members toward successful program delivery
Establish and maintain processes, tools, systems needed to scale clinical development in the disease area: improve efficiency, quality, regulatory compliance
Oversee budgets, resources, timelines, and milestone achievement for disease-area programs. Prioritize between projects; make trade-off decisions as needed
Serve on and provide input to internal RevMed governance / committee structures (e.g., DevLT, DRG, protocol review committees)
Represent RevMed externally: present disease area and molecule development plans, clinical data, and strategy to regulatory agencies, at conferences, in publications
Ensure adherence to GCP, ICH, FDA/EMA (and other relevant health authority) guidelines, quality assurance, safety monitoring, benefit-risk assessment
Define and drive the disease-area clinical vision; integrating translational science, regulatory pathways, and commercial readiness
Lead enterprise portfolio prioritization and investment trade-off decisions through collaboration with R&D, Commercial, and Finance
Qualification
Required
MD, PhD or equivalent advanced biomedical degree with 15+ years experience in pharmaceutical / biotech industry (including clinical development in oncology / solid tumors); academic faculty experience outside of industry considered pending transferability of skills and responsibilities
Extensive oncology clinical development experience, with deep expertise in solid tumors and a demonstrated ability to rapidly build and apply disease-area knowledge (e.g., lung, colon, pancreas) to guide program strategy and execution
Experience authoring and leading clinical development strategies, including label-enabling outcomes, regulatory submissions (e.g., NDA/BLA/MAA) in global settings
Strong scientific credibility: publications in peer-reviewed journals, external recognition (KOLs, conferences)
Proven ability to lead large, cross-functional teams, including both direct and indirect reports; proven ability to mentor, motivate, retain high caliber clinical scientists
Demonstrated ability to manage clinical budgets, timelines, resources; strong decision-making in trade-off situations balancing safety, efficacy, speed, cost
Excellent communication, presentation, interpersonal skills; ability to influence and collaborate with senior management, external stakeholders, regulatory agencies
Experience influencing corporate strategy and external industry direction, including partnerships, senior level interactions, or health authority representation
Organizational scaling experience, including leading through growth, change, and commercialization
Preferred
Experience with biomarker-driven trial design, precision medicine, translational science relevant to cancer
Prior experience building or refining processes, systems, tools for scaling clinical development in a disease area
Experience with commercialization lifecycle, post-approval studies / life-cycle management
Experience interacting with health authorities globally across multiple regions
Experience in M&A / in-licensing or partnering for external assets relevant to disease-area
Successful experience presenting external scientific strategy, communicating to external advisory boards, investigator meetings
Benefits
Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities
Company
Revolution Medicines
Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.
501-1000 employees
H1B Sponsorship
Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$2.25BKey Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M
Leadership Team
Luan Wilfong
Chief Human Resources Officer
Steve Kelsey
President
Recent News
2026-01-09
2026-01-09
Company data provided by crunchbase