Mount Sinai Health System · 3 months ago
Postdoctoral Fellow-MSH-32050-003
New York, NY
Full-time
Onsite
Mid, Senior Level
$72K/yr - $80K/yr
4+ years expMount Sinai Health System is one of the largest academic medical systems in the New York metro area, and they are seeking a Postdoctoral Fellow to lead research in differentiating human pluripotent stem cells into cortical neurons and astrocytes. The role involves managing experimental timelines, supervising lab members, and collaborating on grant proposals while conducting advanced molecular biology techniques and data analysis.
Health CareHospitalMedical
Responsibilities
Leading the differentiation of hPSCs into cortical neurons and astrocytes
Generating and maintaining 3D midbrain organoids for disease modeling and functional assays
Designing and executing assays to evaluate lysosomal activity, polyamine distribution, and α-synuclein accumulation (e.g., DQ-BSA assay, LAMP1 staining, ICC)
Performing confocal imaging, molecular biology (qPCR, Western blot), and image-based phenotyping
Supervising and mentoring junior lab members, including graduate students, research technicians, and interns
Managing experimental timelines, data integrity, and regulatory compliance
Developing and refining standard operating procedures (SOPs) for stem cell and organoid workflows
Leading experimental planning and data analysis using ImageJ, CellProfiler, Prism, and/or R
Preparing manuscripts, figures, and presentations for scientific publications and conferences
Collaborating with the principal investigator on grant proposals, experimental strategy, and lab-wide initiatives
Qualification
Required
A recent Ph.D. graduate with demonstrated experience in any of the following fields: cell biology, molecular biology, biochemistry, neuroscience, and developmental/stem cell biology, bioengineering
Experience in the following research areas: iPSC cell culture and differentiation; molecular and cell biology; CRISPR, bioengineering, confocal microscopy; calcium imaging and optogenetics; mouse models; computational biology, single cell/nuclei RNAseq
4-5 years of experience
Company
Mount Sinai Health System
Mount Sinai Health System delivers integrated medical care, research, and medical education through its network.
10001+ employees
H1B Sponsorship
Mount Sinai Health System has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (3)
2023 (26)
2022 (20)
2021 (6)
2020 (20)
Funding
Current Stage
Late StageTotal Funding
$41.9MKey Investors
National Institutes of HealthHearst Health Prize.Multiple Myeloma Research Foundation
2024-11-11Grant· $7M
2024-06-06Grant· $0.1M
2023-11-02Grant· $7M
Leadership Team
Vincent Tammaro
Executive Vice President and Chief Financial Officer
David Feinberg
Senior Vice President, Chief Marketing and Communications Officer
Recent News
Digital Journal
2026-01-08
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