Genentech · 1 day ago
Biostatistics Oncology Lead, Early Development
South San Francisco, CA
Full-time
Onsite
Senior Level, Lead/Staff
$207K/yr - $384K/yr
15+ years expGenentech is a company driven to innovate and advance science for better healthcare access. The Biostatistics Oncology Lead role involves providing scientific and strategic leadership for biostatistical contributions in early-phase clinical development, ensuring rigorous and innovative statistical approaches are employed across programs.
BiotechnologyLife ScienceManufacturing
Responsibilities
You provide scientific and strategic biostatistics leadership across early phase studies and programs, ensuring methods are rigorous, decision enabling, and aligned
You define fit for purpose statistical approaches for study design, endpoint selection, and data interpretation across exploratory and translational settings
You guide the application of innovative methodologies such as Bayesian methods, simulation, and adaptive designs to support early decision making under uncertainty
You ensure high quality, reproducible statistical deliverables across studies, aligned with internal best practices and external expectations
You act as the biostatistics point of accountability for the therapeutic area within EDB, engaging in program level strategy and planning
You promote consistent, scalable statistical practices by contributing to internal frameworks, standards, and tool development
You represent biostatistics in cross program discussions and EDB leadership forums, helping shape function wide direction and priorities
You advance early development analytics by integrating modern statistical tools, AI/ML, and data science capabilities
You lead, mentor, and develop a high performing team of biostatisticians across early phase programs within the therapeutic area
You foster a culture of scientific excellence, accountability, and continuous learning by setting clear expectations, providing ongoing feedback, and recognizing performance
You create an inclusive and psychologically safe team environment that encourages open dialogue, curiosity, and innovation
You support the professional development of team members through coaching, targeted opportunities, and succession planning
You ensure appropriate resourcing and workload balance across studies and programs, anticipating future needs and adjusting as priorities evolve
You collaborate with Early Development Biometrics and PD-DSA leadership to define role expectations, career paths, and performance standards for statistical talent
You partner with People & Culture (P&C) to attract, retain, and onboard diverse statistical talent aligned with the future needs of early development
You act as a role model for Roche’s leadership commitments, embracing a growth mindset and empowering team members to lead from every seat
Qualification
Required
You hold a PhD or equivalent advanced degree in Statistics, Biostatistics, or a related quantitative discipline
You bring 15+ years of experience in statistical roles in pharmaceutical, biotech, or clinical research settings, including substantial experience in early clinical development
You have a proven track record of statistical leadership across multiple studies and programs, with impact on early phase design, strategy, and decision making
You have strong expertise in clinical trial design, Bayesian and adaptive methods, and statistical modeling under uncertainty
You demonstrate the ability to lead and develop statistical teams, fostering scientific excellence and individual growth
You have a deep understanding of the unique challenges and scientific opportunities in early phase drug development, including exploratory endpoints, high dimensional data, and translational research
You communicate complex statistical concepts clearly and think strategically, translating them into actionable insights
You demonstrate respect for cultural differences when interacting with colleagues in the global workplace
Preferred
Experience leading statistical contributions to early development strategies, including dose finding, proof-of-concept, and translational study design
Familiarity with modern data types and exploratory analysis techniques, including biomarkers, -omics, imaging, or real-world data
Demonstrated application of Bayesian methods, modeling and simulation, or model-informed drug development in early-phase settings
Engagement with regulatory agencies, scientific consortia, or external partners on topics related to early development analytics
Experience shaping internal best practices, frameworks, or standards for statistical excellence and reproducibility
Strong interest in or experience with digital innovation, AI/ML, or advanced data science methods applicable to early-phase research
Proven ability to lead through ambiguity and influence across organizational boundaries in a matrixed and evolving environment
Recognized contributor to internal scientific communities or external forums (e.g., publications, conferences, working groups)
Benefits
A discretionary annual bonus may be available based on individual and Company performance.
This position also qualifies for the benefits detailed at the link provided below.
Company
Genentech
Genentech is a biotechnology research company that specializes in genetic testing and personalized medicines.
10001+ employees
H1B Sponsorship
Genentech has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (167)
2024 (148)
2023 (150)
2022 (178)
2021 (121)
2020 (158)
Funding
Current Stage
Public CompanyTotal Funding
unknown2009-03-26Acquired
1999-07-20IPO
1976-01-01Series Unknown
Leadership Team
Ashley Magargee
CEO
Michael Laird
Vice President
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