iPSC Core Group Leader jobs in United States
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Conception · 2 months ago

iPSC Core Group Leader

Conception is pioneering the future of reproductive biology by generating functional human eggs from induced pluripotent stem cells (iPSCs). They are seeking a motivated iPSC Core Group Leader to manage the iPSC core, ensuring stability and quality across operations while leading a team and collaborating with R&D and Operations.

BiotechnologyHealth CareMedical

Responsibilities

Organize and run the iPSC core day-to-day
Maintain cell banks and execute QC for iPSCs and feeder lines
Track QC results, reagents, lots, consumables, and equipment; manage incubators and hoods in collaboration with Operations
Work closely with Operations to ensure differentiation protocols remain extremely stable and repeatable
Build and document SOPs for routine workflows
Collaborate with the Cell Engineering team to validate, QC, bank, and integrate new cell lines into the core
Establish strong communication loops with R&D teams to manage cell handoffs, define acceptance criteria, and communicate disruptions or delays to maintain quality
Lead, mentor, and grow a small team; set expectations for consistency, documentation, and accountability
Keep junior scientists engaged and motivated on core work; invest in training and mentorship
Coordinate across R&D and Operations to communicate timings, risks, delays, and mitigations proactively
Collaborate with R&D scientists to standardize and scale directed differentiation of at least one lineage, expanding to multiple lines over time
Partner with ML and computational biology experts to explore automated imaging and RNAseq as predictors of long-term culture success
Develop and implement new QC methods for differentiations
Propose innovations to improve cell quality, efficiency, and early risk detection

Qualification

IPSC cultureDifferentiation protocolsCell culture operationsTeam leadershipProactiveCommunicationDetail-oriented

Required

Experience level: PhD or equivalent work experience
Extensive, senior-scientist-level experience with iPSC culture and differentiation protocols to one or more lineages
Proven ability to run organized, traceable, high-quality cell culture operations
Experience mentoring or managing junior scientists
Exceptionally organized, detail-oriented, and proactive
Strong communicator and collaborator
Motivation to build systems that scale from R&D to preclinical and CMC readiness

Preferred

PhD in Cell or Developmental Biology or related field, or Master's with relevant industry experience

Benefits

Competitive pay
Company equity
Excellent healthcare benefits

Company

Conception

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Conception is a company developing the technology to turn skin cells into viable human eggs.

Funding

Current Stage
Early Stage
Total Funding
$20M
2021-11-23Series Unknown· $20M
2020-08-03Seed
2019-05-03Convertible Note

Leadership Team

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Matt Krisiloff
CEO and Co-Founder
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Bianka Seres
Head of Engineering / COO
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Company data provided by crunchbase