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City of Hope · 1 month ago

Assistant Research Professor - Precision Oncology of Gastrointestinal Cancers

Monrovia, CA

Full-time

Onsite

Senior Level

$59/hr - $70/hr

City of Hope is a leading research institution focused on innovative approaches to combat cancer and other life-threatening illnesses. The role involves conducting groundbreaking research on gastrointestinal cancers, including genomic and epigenomic studies, and contributing to various collaborative projects within a multidisciplinary team.

AssociationEducationHealth Care

Comp. & Benefits

Responsibilities

Development of cell-free DNA (mutation and methylation), RNA, and exosomal-based liquid assays for early cancer detection, prognosis, and predictive responses to chemotherapies and targeted drugs

Studying the genetic and epigenetic basis of GI cancers (e.g., aberrant DNA methylation, histone modifications, and non-coding RNAs)

Understanding the biological implications of gut microbiome and its translational application in gastrointestinal cancers

The genetic basis of early-onset colorectal cancer (EO-CRC) and familial/hereditary colorectal cancer

The role of extracellular vesicles/exosomes in cancer pathogenesis and their role as disease biomarkers

The role of the tumor microenvironment, stem cells, immune regulation, and identification of novel targeted therapies

Cancer prevention and adjunctive role of natural and integrative therapy approaches

Qualification

OncologyCancer biologyTranslational researchImmunologyMolecular researchProject developmentScientific rigorHigh-impact publicationsFunding acquisitionMentoring

Required

PhD, MD, or MD/PhD, with a strong background and profound knowledge in the field of oncology, cancer biology, immunology, or immunotherapy

Prior molecular, cancer biology, and/or translational research experience and evidence of project development and supervision of post-doctoral fellows and technical staff

Evidence of scientific rigor and excellence as documented by high-impact peer-reviewed publications, as a first/lead author

Evidence for obtaining successful funding from various foundations or other extramural resources

Documented evidence of mentoring post-docs, research associates, and others in a research laboratory environment