Amgen · 2 months ago
Senior Scientist – Research Computational Biology (ARIA)
United States
Full-time
Hybrid
Mid, Senior Level
3+ years expAmgen is a leading biotechnology company dedicated to serving patients living with serious illnesses. The Senior Scientist in Research Computational Biology will apply expertise in data science and disease biology to advance the therapeutic pipeline by identifying and validating transformative therapeutic targets.
BiotechnologyHealth CareManufacturingPharmaceutical
Responsibilities
Extracting biological insight from complex multi-modal omics and screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses
Developing and leveraging methods/platforms to discover, prioritize, and validate targets across diverse diseases and therapeutic modalities
Innovative research in close partnership with Amgen therapeutic area scientists, spanning both internal pipeline programs and external partnerships
Partnering with our data science and information systems teams to incorporate tools and analyses developed within ARIA Computational Biology into integrated R&D platforms
Qualification
Required
Doctorate in computational biology, bioinformatics, data science, or a related discipline [and relevant post-doc where applicable]
Master's degree and 3 years of relevant research experience
Bachelor's degree and 5 years of relevant research experience
Preferred
Strong programming skills (Python, R, Linux/Unix), familiarity with cloud computing environments, HPC, and collaborative coding practices (e.g., Git)
Track record of designing and implementing creative and holistic computational strategies to address challenging research questions
Demonstrated expertise in the analysis and interpretation of single cell omics data
Excellent presentation and communication skills to convey complex findings to diverse audiences
Self-starter with a collaborative mentality and a drive for continuous growth
Strong background in cardiometabolic disease and/or immunology, including application to the interpretation of single-cell data
Experience leveraging and fine-tuning transcriptional foundation models, LLMs, and biomedical knowledge graphs to further research goals
Familiarity with public data resources (e.g. DepMap, Human Cell Atlas, TCGA, GTEx, and Tahoe-100M) frequently used to augment analyses of internally generated data
Experience developing and deploying tools and pipelines to endpoints such as interactive portals (e.g. RShiny apps), workflow management systems (e.g Nextflow), and agentic frameworks
Benefits
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible
Company
Amgen
Amgen is a biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases.
10001+ employees
H1B Sponsorship
Amgen has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (429)
2024 (485)
2023 (485)
2022 (540)
2021 (460)
2020 (444)
Funding
Current Stage
Public CompanyTotal Funding
$28.5B2022-12-12Post Ipo Debt· $28.5B
1983-06-17IPO
Leadership Team
Robert Bradway
Chairman and Chief Executive Officer
Jay Bradner
Executive Vice President of R&D, and Chief Scientific Officer
Recent News
2026-01-13
Genetic Engineering News
2026-01-12
Company data provided by crunchbase