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Zephyr AI · 3 months ago

Bioinformatics Scientist

United States

Full-time

Remote

Mid, Senior Level

Zephyr AI is building an innovative AI platform to change the way we treat cancer and other chronic diseases. They are seeking a talented Bioinformatics Scientist to develop and deploy computational engines and bioinformatics pipelines for processing massive Next-Generation Sequencing datasets, contributing to cancer research and patient care.

Artificial Intelligence (AI)BiotechnologyMedical

H1B Sponsor Likely

Responsibilities

Design, build, and maintain robust, scalable bioinformatics pipelines for processing and analyzing next-generation sequencing (NGS) data (e.g., WGS, WES, RNA-seq, ctDNA/liquid biopsy)

Perform rigorous quality control and statistical analysis of high-throughput biological data to ensure data integrity and generate actionable insights

Integrating genomics, transcriptomics, and real-world clinical data (EHR, claims) to provide actionable biological insights

Write clean, well-documented, and production-ready Python code, leveraging modern workflow orchestration tools like Dagster and/or Nextflow

Collaborate closely with computational biologists and machine learning scientists to prepare datasets for model training. Clearly communicate complex computational results and biological insights to colleagues with diverse scientific backgrounds

Qualification

NGS data analysisPython programmingBioinformatics pipelinesMachine LearningCloud ComputingStatistical analysisCollaborationCommunication skillsProblem-solving mindsetOrganizational skills

Required

Ph.D. in Bioinformatics, Computational Biology, Genetics, or a related quantitative field. (Exceptional candidates with an M.S. or B.S. and relevant industry experience will also be considered)

Deep expertise in NGS data analysis, including a strong understanding of standard tools (e.g., BWA, STAR, GATK, SAMtools) and algorithms for variant calling, expression quantification, and quality control

Proficiency in Python and its scientific computing ecosystem (pandas, NumPy, scikit-learn)

Experience in precision oncology, immuno-oncology, liquid biopsy analysis (ctDNA, MRD), or AI-driven drug discovery

Solid understanding of molecular biology, genetics, and genomics

A collaborative, problem-solving mindset and excellent communication skills

Preferred

Machine Learning: Experience with or a strong understanding of machine learning concepts and their application to biological data

Pipeline & Workflow Orchestration: Proven experience building and managing production-grade bioinformatics pipelines using workflow managers such as Dagster and Nextflow

Public Datasets: Hands-on experience with large-scale public cancer genomics datasets (e.g., TCGA, GENIE, DepMap)

Publication Record: A track record of peer-reviewed publications in relevant fields

Software Engineering Practices: Familiarity with software development best practices, including version control (Git), containerization (Docker/Singularity), and CI/CD principles

Cloud Computing: Experience with cloud computing environments (AWS or Azure) and services

Benefits

United Healthcare PPO, HMO, and HDHP plans > 100% company paid for you + family

Dental (including orthodontic coverage) > 4 carriers, 100% company paid for you + family

Vision > 2 carriers, 100% company paid for you + family

Health Savings Account ( HSA) + Flexible Spending Account (FSA)

Basic Life and AD&D Insurance > 100% company paid

Voluntary benefits: short term and long term disability, supplemental AD&D, supplemental life, pet insurance

Paid maternity and paternity leave

Flexible paid time off

15 Paid holidays

401(k) program

Work from home + cell phone/internet reimbursement

Unlimited 1:1 tax advisory sessions with our equity management team

Employee referral bonus

Employee assistance program (EAP)

Opportunities for advancement

Company

Zephyr AI

Zephyr AI is a healthcare technology company that reshapes traditional approaches to drug discovery and precision medicine.

Founded in 2020

Fairfax Station, Virginia, USA

11-50 employees

https://www.zephyrai.bio

H1B Sponsorship

Zephyr AI has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

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Trends of Total Sponsorships

2025 (1)

2022 (2)