Eli Lilly and Company · 19 hours ago
Scientific Advisor - ADME Project Leadership for Biologics
Indianapolis, IN
Full-time
Onsite
Mid, Senior Level
$152K/yr - $244K/yr
1+ years expEli Lilly and Company is a global healthcare leader headquartered in Indianapolis, Indiana. They are seeking a dedicated scientist for their ADME team to lead and innovate in the discovery and clinical development of biologics and drug conjugates, focusing on ADME studies to support the Lilly portfolio.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Lead and innovate in a multidisciplinary collaborative environment with primary responsibility for ADME studies to support preclinical and clinical development of the Lilly portfolio
Design and implement hypothesis driven studies to answer ADME, PK/PD and clinical pharmacology questions
Integrate ADME, PK and PK/PD endpoints with discovery biology data to define structure activity- and structure-property-relationships to guide drug delivery and optimization strategies
Engage, innovate, and collaborate with colleagues and interdisciplinary teams
Lead the preparation of regulatory communication and documents to support clinical development, new drug applications (NDA and BLA) and line extensions and interact with regulatory agencies worldwide
Build and foster relationships through coaching and mentorship with fellow scientists
Possess excellent written and verbal technical communication skills and the ability to lead, guide and influence teams in decision making
Qualification
Required
Ph.D. in Biology, Cellular or Molecular Biology, Biochemistry, Pharmaceutical Sciences, Pharmacokinetics or a related scientific field; experience in the discovery and development of biological-therapeutics highly preferred
High learning agility and a keen ability to derive and efficiently test ADME and DMPK hypotheses for novel molecules with particular emphasis on antibodies
Strong working knowledge in fundamental pharmaceutics, pharmacokinetics and ADME principles especially as they relate to biologics such as antibodies and conjugated molecules
Understanding of contemporary pharmaceutical regulatory guidance and expectations
Skills to integrate internal and external laboratory and other experimental resources through high quality scientific associations
Agile interrogation of diverse data (e.g., in silico, in vitro, in vivo) to derive mechanistic understanding of drug action and performance characteristics
Lead and innovate in a multidisciplinary collaborative environment with primary responsibility for ADME studies to support preclinical and clinical development of the Lilly portfolio
Design and implement hypothesis driven studies to answer ADME, PK/PD and clinical pharmacology questions
Integrate ADME, PK and PK/PD endpoints with discovery biology data to define structure activity- and structure-property-relationships to guide drug delivery and optimization strategies
Engage, innovate, and collaborate with colleagues and interdisciplinary teams
Lead the preparation of regulatory communication and documents to support clinical development, new drug applications (NDA and BLA) and line extensions and interact with regulatory agencies worldwide
Build and foster relationships through coaching and mentorship with fellow scientists
Possess excellent written and verbal technical communication skills and the ability to lead, guide and influence teams in decision making
Preferred
Industry (Pharma/Biotech) experience (1- 7 years) in the preclinical evaluation of biologics and or hybrid modalities, as well as relevant ADME project leadership experience
Understanding of and experience with immunoassays, and/or LC/MS bioanalytical methodology
Detailed understanding of pharmacokinetics, ADME and proficiency to communicate theory and concepts clearly
Experience in drug discovery and development
Experience with PK/PD modeling and/or bio-distribution
Ability to balance multiple projects and handle competing responsibilities
Collaborative team behaviors and aspiration to build and sustain relationships with R&D customers and the wider scientific community
Excellent oral and written communication skills
Experience authoring regulatory and technical reports
Benefits
Company bonus
Eligibility to participate in a company-sponsored 401(k)
Pension
Vacation benefits
Eligibility for medical, dental, vision and prescription drug benefits
Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
Life insurance and death benefits
Certain time off and leave of absence benefits
Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
Company
Eli Lilly and Company
We're a medicine company turning science into healing to make life better for people around the world.
10001+ employees
H1B Sponsorship
Eli Lilly and Company has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
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Trends of Total Sponsorships
2025 (514)
2024 (236)
2023 (167)
2022 (133)
2021 (57)
2020 (52)
Funding
Current Stage
Public CompanyTotal Funding
$6.5M2024-02-12Post Ipo Debt· $6.5M
1978-01-13IPO
Leadership Team
David Ricks
Chair, CEO
Lucas Montarce
Executive Vice President and Chief Financial Officer
Recent News
2026-01-12
2026-01-12
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