Twist Bioscience · 3 months ago
Manufacturing Lead - IgG Production
USA - Portland, OR
Full-time
Hybrid
Mid, Senior LevelTwist Bioscience is a biotechnology company specializing in DNA synthesis and related products. The Manufacturing Lead will oversee manufacturing operations, guide associates, and ensure production schedules are met while maintaining high-quality standards in a fast-paced environment.
B2BBiotechnologyChemicalHealth CareLife Science
Responsibilities
Assisting the production supervisor and guiding the work performed on the manufacturing floor by manufacturing associates
Troubleshooting all processes related to manufacturing process and instrumentation
Taking responsibility for daily operations when the supervisor is not available
Maintaining daily operations w/ or w/o the supervisor (equipment maintenance, fulfill production request, retain review)
Reviewing time sensitive material and calendar events
Overseeing material inventory and waste management activities for the shift
Monitoring the flow of intermediate products through the Manufacturing Execution System (MES) and notifying the supervisor of any discrepancies
Reviewing JIRA tickets with supervisor to create action items
Enforcing checklist and auditing activities which are built into the production process
Training new laboratory manufacturing associates
Working in the laboratory and performing any process tasks
Manufacturing high quality custom oligo containing products in a high throughput MFG lab according to established SOPs
Operating laboratory equipment and liquid handling robots (Hamilton Stars, centrifuges, sealers, thermocyclers, spectrometers, Illumina Next-Gen sequencers etc.)
Effectively using molecular and cell biology processes and techniques, especially PCR, DNA quantitation, purification and cloning
Maintain thorough, accurate and detailed documentation of all work performed using existing document templates and applications
Updating and writing work instructions and documentation
Working independently and in a safe manner
Paying great attention to detail and yielding consistent results
Performing troubleshooting and handling process deviations correctly
Analyzing data outcomes from manufacturing steps and deciding on or recommending a course of action
Following lean manufacturing, ISO and GMP practices
Qualification
Required
Bachelors/Associates degree in biology, chemistry, biochemistry: degree preferred but will consider candidates with relevant laboratory experience
Familiarity or prior experience in a manufacturing environment
Good written and verbal skills
Attention to detail
Good computer skills and comfort in using computers for all aspects of MFG, experience with excel and word, Jira/Confluence, web based or similar programs
Ability to work in a controlled laboratory environment
Must be able to stand for long periods of time while performing duties
Must be able to work safely with chemicals and hazardous materials
Must be able to lift up to 20 lbs
Must have flexibility to work outside of regular work hours/work a flexible shift as needed
Company
Twist Bioscience
Twist Bioscience is a biotechnology company that offers synthetic DNA solutions, gene synthesis, and variant libraries.
Founded in 2013
501-1000 employees
H1B Sponsorship
Twist Bioscience has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (18)
2024 (14)
2023 (22)
2022 (19)
2021 (4)
2020 (6)
Funding
Current Stage
Public CompanyTotal Funding
$553.11MKey Investors
Capital World InvestorsBiomatics Capital PartnersIllumina
2022-02-09Post Ipo Equity· $250M
2020-01-27Post Ipo Equity· $50M
2018-10-30IPO
Leadership Team
Emily Leproust
CEO
Siyuan Chen
Chief Technology Officer
Recent News
Genetic Engineering News
2026-01-17
2026-01-16
Company data provided by crunchbase