AbbVie · 5 hours ago
Senior Scientist I (PK/PD Modeling)
South San Francisco, CA
Full-time
Onsite
Senior Level, Lead/Staff
8+ years expAbbVie is a global organization focused on discovering and delivering innovative medicines to address serious health issues. They are seeking a Senior Scientist I to provide mechanistic and translational modeling support across various disease areas, collaborating closely with project teams to advance their pipeline from Discovery to early Development.
BiotechnologyFinancial ServicesHealth CareMedicalPharmaceuticalVenture Capital
Responsibilities
Develop and implement innovative, quantitative analyses and strategies for translational modeling across Discovery and Development projects
Liaise with Discovery biology, pharmacology, toxicology, biomarker, QTAS and clinical scientists to generate data and knowledge supporting the generation and implementation of translational models
Establish and maintain effective collaborations with key peer and team stakeholders within QTAS, Discovery and Clinical to facilitate knowledge and data integration for target prioritization, biomarker selection, candidate selection, guidance in (pre)clinical study design, human dose prediction and calculation of therapeutic index
Effectively communicate on strategies related to drug metabolism and pharmacokinetics (DMPK) and translational modeling and simulation
Maintain awareness of emerging literature and science in computational approaches and applications
Qualification
Required
Bachelors (B.S.), Masters (M.S.), or Doctorate (Ph.D.) in in chemical, mechanical, or biomedical engineering; applied mathematics; quantitative pharmaceutical sciences or a related field, with at 10+ years of experience and Bachelors Degree, OR 8+ years of experience and Masters Degree., or Ph.D. and no experience necessary
Hands-on experience with relevant modeling software and programming languages including MATLAB/SimBiology, R, Python, WinNonLin/Phoenix, etc. is required
Understanding of small or large molecule drug modalities and relevant analytical methods for measuring drug and biomarker levels in preclinical and clinical study samples is highly desired
Passion for data analysis, solving technical problems and applying new technologies to further scientific goals and answer key scientific questions enabling informed decision-making
Publication record demonstrating PK/PD or systems modeling examples is highly desired
Highly-motivated, self-driven and results-oriented person with excellent communication and presentation skills, capable of both leading and being lead
High degree of flexibility in adapting to different projects and personalities as well as excellent networking and relationship-building skills (both internal and external) required
Must have strong communication skills and the ability to effectively communicate with both internal and external stakeholders, and to audiences of diverse backgrounds
Prior experience in an experimental in vitro or in vivo biology field is desired
Interest in developing skills to support projects as a QTAS project representative in future is highly desired
Preferred
Doctorate (Ph.D.) in chemical, mechanical, or biomedical engineering; applied mathematics; quantitative pharmaceutical sciences or a related field, with 1-3 years of pharmaceutical industry experience
Benefits
Paid time off (vacation, holidays, sick)
Medical/dental/vision insurance
401(k)
Company
AbbVie
AbbVie is a biopharmaceutical company focused on immunology, oncology, neuroscience, virology, and aesthetics. It is a sub-organization of AbbVie.
10001+ employees
H1B Sponsorship
AbbVie has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (273)
2024 (190)
2023 (225)
2022 (284)
2021 (186)
2020 (186)
Funding
Current Stage
Public CompanyTotal Funding
$15B2024-02-27Post Ipo Debt· $15B
2023-03-08Post Ipo Equity· $0.25M
2012-12-20IPO
Leadership Team
Robert Michael
Chairman of the Board and Chief Executive Officer
Micah Bregman
Vice President, Global Strategy and Pipeline, Allergan Aesthetics
Recent News
Pharmaceutical Technology
2026-01-13
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