Penn State University · 3 months ago
Researcher- Heart and Vascular Institute
Hershey, PA
Full-time
Onsite
Senior LevelPenn State University is seeking a Researcher for its Heart and Vascular Institute in Hershey, PA. The role involves studying the interactions between estrogen receptors and drug molecules using various lab techniques, and responsibilities include performing cardiac analyses, maintaining cell lines, and overseeing animal lines.
Higher Education
Responsibilities
Perform small animal cardiac structure and functional analysis. This includes independently performing small animal echocardiography, real-time measurements of function using 2D, M-mode, & Doppler technology, as well as data analysis. Tissue harvesting, staining and flow analysis for immune cell subsets. Perform data analysis, and finally, write manuscripts/grants originating from this data
Maintain cell line, perform pharmacological assays of cell lines with the microplate reader, perform Western blotting assays and quantitative RT-PCR assays related to estrogen signaling and novel small molecule ligands
Independently monitor and carry out oversight of animal lines including transgenic mice colony maintenance, employing gel electrophoresis and PCR techniques. Analyze and plot data obtained from the assays performed
Provide training of other technicians to ensure that duties above are properly and aptly executed
Qualification
Required
Doctoral degree with expertise in molecular biology
Experience with in-vivo and in-vitro models of inflammation testing
Computational methods of drug design and docking
Experience with cell culture techniques
Demonstrated ability to isolate and culture primary cells
Effective knowledge of lab practices and procedures in animal handling, dissection, Western blotting, PCR, fluorescence imaging, sub-cloning, and transfection
Ability to work independently with minimal supervision by PI
Ability to perform routine duties using established procedures with coordination and effective communication with the PI
Ability to independently develop and implement laboratory policies
Excellent verbal and written communication skills for manuscript and grant preparation
Ability to contribute to the optimization of experimental procedures that require novel approaches
Benefits
Comprehensive medical, dental, and vision coverage
Robust retirement plans
Generous 75% tuition discount, available to employees as well as eligible spouses and children
Company
Penn State University
There’s a reason Penn State consistently ranks among the top one percent of the world’s universities.
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10001+ employees
Funding
Current Stage
Late StageLeadership Team
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