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Iambic Therapeutics · 2 months ago

Sr Associate Scientist I or II, Medicinal Chemistry

San Diego HQ

Full-time

Onsite

Mid, Senior Level

$84K/yr - $120K/yr

3+ years exp

Iambic Therapeutics is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. The Senior Associate Scientist will work within a dynamic team, focusing on the design, synthesis, and optimization of chemical compounds while collaborating with various scientific disciplines throughout the drug discovery process.

Artificial Intelligence (AI)Machine LearningSoftwareTherapeutics

Responsibilities

Design, synthesize, purify, and characterize chemical compounds (10 mg–5 g scale) using modern analytical techniques such as LCMS, HPLC, and NMR, employing both individual and automated parallel synthesis approaches

Identify and optimize reaction conditions using screening kits and other streamlined methodologies

Collaborate with the high-throughput experimentation team to ensure the successful execution of parallel chemistry experiments

Analyze biological and ADME-PK data using cheminformatics tools and contribute to data-driven discussions and strategic planning

Partner with computational chemists to leverage machine learning insights for efficient execution of the design–make–test cycle and platform development

Present results to project teams and senior leadership, clearly communicating data, implications, and recommendations