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Goldbelt Apex LLC · 8 hours ago

Senior Therapeutics Discovery Technician

Fort Detrick, MD

Full-time

Onsite

Mid, Senior Level

$80K/yr - $90K/yr

3+ years exp

Goldbelt Apex LLC is a data-focused company dedicated to process and quality in healthcare IT. The Senior Therapeutics Discovery Technician will provide senior laboratory support for research efforts, including high-throughput screening projects and microbiological experiments in BSL-2, BSL-3, and BSL-4 environments.

Responsibilities

Assist in the planning, development, execution and evaluation of high-throughput screening projects for the antibacterial, anti-viral, and anti-toxin therapeutic areas and assist in the development of novel assays/methods for various programs. This includes basic cell culture to support these efforts. Shall assist in screening of molecular compound libraries for therapeutic efficacy to support MCM development

The Contractor shall perform both in vitro and in vivo microbiological experiments designed to evaluate therapeutic compounds for antibacterial/antiviral/antitoxin activity. In vitro assays include enzymatic assays, cell-based phenotypic and reporter assays. Minimum Inhibitory Concentration (MIC) and plaque assays. Shall perform standard molecular biology techniques to support development of these assays

The Contractor shall support mouse studies when required. Shall assist with inoculations of animals, collecting specimens for processing, and analysis of those specimens. Analysis may include development and conduct of immunological procedures including Enzyme Linked immunoassay (ELISA), Western blot, and Mesoscale Discovery based assays

The Contractor shall assist in the preparation of technical reports, standard operating procedures, and manuscripts relating to their research efforts. The Contractor may be expected to present research findings at 1-2 scientific conference per year as needed and CONUS travel may be required. Contractor shall present results in written and oral format publicly and internally as requested

The Contractor shall be responsible for assessing and maintaining laboratory supplies in BSL-2, BSL-3 and BSL-4 laboratories. Shall assess supplies and ensure supply orders are coordinated with Division resources. Shall ensure that all assigned laboratory space is orderly and compliant with all regulatory guidance

The Contractor shall perform operations and training in animal manipulations. Contractor shall support animal studies (mouse, hamsters, guinea pigs, etc.) for funded projects. Contractor shall be experienced with handling both bacterial and viral pathogens for in vitro and in vivo studies with preferred experience in BSL-2, BSL-3 and BSL-4 biocontainment labs

Contractor shall provide the TPOC a Research Technical Report NLT the last day of each month

Contractor shall communicate to the Lead/PI or assigned TPOC as applicable, unexpected experimental data/results and assist in the troubleshooting or root cause analysis. Contractor shall communicate to the TPOC any laboratory or other work-related issues. Contractor shall communicate with internal maintenance or external vendors for technical support and troubleshooting

Contractor shall maintain an orderly laboratory environment in compliance with regulations. Contractor shall coordinate ordering of supplies with division staff. Contractor shall assist in training new personnel including students and other technicians as needed

Perform other duties as assigned

Qualification

BSL-2 laboratory experienceBSL-3 laboratory experienceBSL-4 laboratory experienceMicrobiological experimentsMolecular biology techniquesAnimal manipulationLaboratory practiceQuality assuranceAerobiologyClinical pathologyHistopathologyElectron microscopyConfocal microscopyTechnical report writing

Required

Bachelor's degree with 7+ years of related experience or a master's degree and 3+ years of related experience

Ability to obtain and maintain a SECRET security clearance eligibility, with no access to classified information, is required

Enroll in the Personnel Reliability Program (PRP), if required

Specialized skills may be required, including but not limited to, aerobiology, clinical pathology, electron or confocal microscopy, histopathology, quality assurance, and good laboratory practice

Ability to Independently reads, understands, and executes techniques, procedures, and plans to meet requirements of quality standards, national standards of research technical accuracy, other relevant written guidelines