Revolution Medicines · 3 hours ago
Scientist II, Clinical Bioinformatics
San Francisco Bay Area
Full-time
Onsite
Entry, Mid Level
$128K/yr - $160K/yr
2+ years expRevolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. The Scientist II, Clinical Bioinformatics will analyze and interpret molecular and clinical data to identify and validate predictive biomarkers, contributing to drug development projects in a collaborative environment.
Health CareLife ScienceMedical
Responsibilities
Integrate multiple data sources including circulating tumor DNA, patient enrollment data, molecular profiling (RNA/DNA sequencing outputs), multiplex immunohistochemistry to identify and validate new biomarkers for candidate drugs
Work with internal groups, contract research organizations and collaborators to deliver validated biomarker data and analysis
Support the development of biomarker related aspects of the trial design where bioinformatic analysis is required, including developing and executing on biomarker and statistical analysis plans
Work with biomarker scientists to support analysis of biomarker readouts (summary statistics, and visualization of efficacy in molecular subgroups)
Collaborate with preclinical bioinformaticians to design, analyze and interpret experiments to validate biomarkers, understand compound mechanism of action and resistance, and identify biomarkers for patient selection/stratification
Qualification
Required
M.S. or Ph.D. in bioinformatics, data science or a related field with emphasis on biological data analysis
2+ years of pharmaceutical or biotech experience in bioinformatics focused on oncology, or related field
Proficiency and experience programming using R and/or Python
Proficiency in statistical models and analysis of clinical data. Some ML experience a strong plus
Proficiency in visualizations and faceting of molecular data necessary (oncoplots, heatmaps, PCA, etc.)
Experience with efficacy, baseline demographic, and other outcome data generated in a clinical trial
Experience with statistical methods i.e. survival analysis, and causal inference
Expertise in bioinformatic analysis of cancer signaling pathways and driver mutations
Experience in tools to analyze cancer genomics data types (RNA, WES, ctDNA, etc) and common tool outputs (GATK, Salmon, OncoKB, VEP, etc.)
Preferred
Previous biostats and/or translational medicine experience in phase 3 trials strongly preferred
Development with professional software development systems and methods (IDEs, git, ticketing systems)
Familiarity with large public/private genomic data sets (GDC, TCGA, etc.)
Familiarity with clusters, containers, and cloud computing infrastructure for data processing, analysis, and storage
Experience in tools to analyze cancer genomics datasets (GATK, Salmon, OncoKB, VEP, etc.)
Benefits
Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities
Company
Revolution Medicines
Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.
501-1000 employees
H1B Sponsorship
Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$2.25BKey Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M
Leadership Team
Luan Wilfong
Chief Human Resources Officer
Steve Kelsey
President
Recent News
2025-12-18
2025-12-18
Company data provided by crunchbase