Senior / Principal Computational Biologist jobs in United States
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Somite AI · 2 months ago

Senior / Principal Computational Biologist

Cellular Intelligence, formerly Somite AI, is a venture-backed company focused on developing AI foundation models for human stem cells to drive novel cell therapies. The Senior Computational Biologist will create pipelines, models, and perform research on large-scale single-cell datasets to contribute to groundbreaking cell replacement technologies.

Artificial Intelligence (AI)Biotechnology
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H1B Sponsor Likelynote

Responsibilities

Drive new research directions at the interface of bioinformatics and AI-powered stem cell biology
Develop and optimize computational biology pipelines for preprocessing, analysis, modeling and interpretation of high-dimensional transcriptomic data
Stay at the forefront of computational biology, keeping up with state-of-the-art techniques in developmental biology, single-cell multi-modal analysis and spatial transcriptomics
Operate autonomously in a fast-moving startup, helping shape Cellular Intelligence’s computational biology roadmap
Mentor and provide technical guidance to team members, fostering collaboration and knowledge sharing across disciplines
Collaborate closely with other computational biologists, machine learning researchers, and software engineers to build robust, scalable solutions

Qualification

Computational BiologyBioinformaticsPythonLarge-scale Genomic AnalysisStatistical SkillsMachine LearningPassion for Data-driven BiologyCollaborationMentoring

Required

PhD in Computational Biology, Bioinformatics, Computer Science, or a related field
3+ years of experience analyzing large-scale genomic and transcriptomic datasets, such as single cell RNA-seq and spatial omics
Solid computational and statistical skills, with demonstrated experience in high-dimensional biological data analysis
Strong programming skills and experience developing robust products, preferably in Python
Passion for data-driven biology and its potential to transform healthcare

Preferred

Strong domain knowledge in developmental biology or stem cell research (highly advantageous)
2+ years of experience in non-academic industry setting
Prior experience in a startup or fast-paced environment
Experience in machine learning, and and developing models over biological data
Strong publication record in top journals

Benefits

Enjoy a competitive salary and benefits package, including flexible work options

Company

Somite AI

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Somite.ai is developing AI foundation models for human stem cells to drive novel cell therapies at scale.

H1B Sponsorship

Somite AI has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (2)

Funding

Current Stage
Early Stage
Total Funding
$104.79M
Key Investors
AMD VenturesKhosla VenturesTechAviv
2025-08-20Series Unknown· $47.5M
2025-05-13Series A· $47M
2024-04-10Pre Seed· $10.29M

Leadership Team

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Micha Y. Breakstone
Co-founder and CEO
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Allon Klein
Co-Founder
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Recent News

Company data provided by crunchbase